ArticleAIDS research and treatment2013
Developing multipurpose reproductive health technologies: an integrated strategy.
Article in AIDS research and treatment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Long-acting injectable multipurpose prevention technology for prevention of HIV and unplanned pregnancy.Journal of controlled release : official journal of the Controlled Release Society · 2023Article
- Multipurpose Prevention Technologies: Oral, Parenteral, and Vaginal Dosage Forms for Prevention of HIV/STIs and Unplanned Pregnancy.Polymers · 2021Review
- Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women.EBioMedicine · 2021Article
- Towards a roadmap to advance non-hormonal contraceptive multipurpose prevention technologies: strategic insights from key stakeholders†.Biology of reproduction · 2020Review
- Pharmaceutical Approaches to HIV Treatment and Prevention.Advanced therapeutics · 2018Article
- A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo.PloS one · 2016Article
- Multipurpose prevention technologies: the future of HIV and STI protection.Trends in microbiology · 2015Review
- Strategies for preventing mucosal cell-associated HIV transmission.The Journal of infectious diseases · 2014Review
- Ethical issues for late-stage trials of multipurpose prevention technologies for HIV and pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2014Article
- Promoting reproductive options for HIV-affected couples in sub-Saharan Africa.BJOG : an international journal of obstetrics and gynaecology · 2014Article
- Intravaginal flux controlled pump for sustained release of macromolecules.Pharmaceutical research · 2014Article
- HIV prevention and research considerations for women in sub-Saharan Africa: moving toward biobehavioral prevention strategies.African journal of reproductive health · 2014Article
- Young women's contraceptive microbicide preferences: associations with contraceptive behavior and sexual relationship characteristics.Perspectives on sexual and reproductive health · 2014Article
- Antibody-based concepts for multipurpose prevention technologies.Antiviral research · 2013Review
- How much demand for New HIV prevention technologies can we really expect? Results from a discrete choice experiment in South Africa.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
women worldwide confront two frequently concurrent reproductive health challengesthe need for contraception and for protection from sexually transmitted infections, importantly HIV/AIDS. While conception and infection share the same anatomical site and mode of transmission, there are no reproductive health technologies to date that simultaneously address that reality. Relevant available technologies are either contraceptive or anti-infective, are limited in number, and require different modes of administration and management. These "single-indication" technologies do not therefore fully respond to what is a substantial reproductive health need intimately linked to pivotal events in many women's lives. This paper reviews an integrated attempt to develop multipurpose prevention technologies-"MPTs"-products explicitly designed to simultaneously address the need for both contraception and protection from sexually transmitted infections. It describes an innovative and iterative MPT product development strategy with the following components: identifying different needs for such technologies and global variations in reproductive health priorities, defining "Target Product Profiles" as the framework for a research and development "roadmap," collating an integrated MPT pipeline and characterizing significant pipeline gaps, exploring anticipated regulatory requirements, prioritizing candidates for problem-solving and resource investments, and implementing an ancillary advocacy agenda to support this breadth of effort.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.