ArticleMediators of inflammation2013
The serum IL-6 profile and Treg/Th17 peripheral cell populations in patients with type 1 diabetes.
Article in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes.Journal of translational medicine · 2016Trial
- T helper 17 cells and interleukin-17 immunity in type 1 diabetes: From pathophysiology to targeted immunotherapies.World journal of diabetes · 2025Review
- Mini-Review: Tregs as a Tool for Therapy-Obvious and Non-Obvious Challenges and Solutions.Cells · 2024Review
- Article
- Molecular Markers of Blood Cell Populations Can Help Estimate Aging of the Immune System.International journal of molecular sciences · 2023Review
- Anti-CD20 therapy ameliorates β cell function and rebalances Th17/Treg cells in NOD mice.Endocrine · 2022Article
- Type 1 Diabetes Mellitus in the SARS-CoV-2 Pandemic: Oxidative Stress as a Major Pathophysiological Mechanism Linked to Adverse Clinical Outcomes.Antioxidants (Basel, Switzerland) · 2021Review
- Relevance of Essential Trace Elements in Nutrition and Drinking Water for Human Health and Autoimmune Disease Risk.Nutrients · 2020Review
- Proteins of TNF-α and IL6 Pathways Are Elevated in Serum of Type-1 Diabetes Patients with Microalbuminuria.Frontiers in immunology · 2018Article
- Th9 and Th22 immune response in young patients with type 1 diabetes.Immunologic research · 2016Article
- Allium hookeri root protects oxidative stress-induced inflammatory responses and β-cell damage in pancreas of streptozotocin-induced diabetic rats.BMC complementary and alternative medicine · 2016Article
- Altered platelets' morphological parameters in children with type 1 diabetes – a case-control study.BMC endocrine disorders · 2015Article
- Th17 Cells in Type 1 Diabetes: Role in the Pathogenesis and Regulation by Gut Microbiome.Mediators of inflammation · 2015Review
- Alteration of regulatory T cells in type 1 diabetes mellitus: a comprehensive review.Clinical reviews in allergy & immunology · 2014Review
- Increased Th22 cells are independently associated with Th17 cells in type 1 diabetes.Endocrine · 2014Article
- Resveratrol Ameliorates Diabetes-induced Renal Damage through Regulating the Expression of TGF-β1, Collagen IV and Th17/Treg-related Cytokines in Rats.The West Indian medical journal · 2014Article
- Ageing and myeloid-derived suppressor cells: possible involvement in immunosenescence and age-related disease.Age (Dordrecht, Netherlands) · 2014Review
- Th9/IL-9 profile in human echinococcosis: their involvement in immune response during infection by Echinococcus granulosus.Mediators of inflammation · 2014Article
- IVS1 -397T>C estrogen receptor α polymorphism is associated with low-grade systemic inflammatory response in type 1 diabetic girls.Mediators of inflammation · 2014Article
- Immunological mechanisms in the pathophysiology of non-alcoholic steatohepatitis.International journal of molecular sciences · 2013Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17/Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.