ArticleBioEssays : news and reviews in molecular, cellular and developmental biology2013
Modeling and simulation of biological systems from image data.
Article in BioEssays : news and reviews in molecular, cellular and developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
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- Numerical Model for Cerebrovascular Hemodynamics with Indocyanine Green Fluorescence Videoangiography.Journal of Korean Neurosurgical Society · 2023Article
- Design centering enables robustness screening of pattern formation models.Bioinformatics (Oxford, England) · 2022Article
- Stability selection enables robust learning of differential equations from limited noisy data.Proceedings. Mathematical, physical, and engineering sciences · 2022Article
- VascuViz: a multimodality and multiscale imaging and visualization pipeline for vascular systems biology.Nature methods · 2022Article
- A C++ expression system for partial differential equations enables generic simulations of biological hydrodynamics.The European physical journal. E, Soft matter · 2021Article
- Towards a physical understanding of developmental patterning.Nature reviews. Genetics · 2021Review
- Tracing the footsteps of autophagy in computational biology.Briefings in bioinformatics · 2021Article
- pSSAlib: The partial-propensity stochastic chemical network simulator.PLoS computational biology · 2017Article
- Article
- Parameter identification problems in the modelling of cell motility.Journal of mathematical biology · 2015Article
- Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh.Nature protocols · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This essay provides an introduction to the terminology, concepts, methods, and challenges of image-based modeling in biology. Image-based modeling and simulation aims at using systematic, quantitative image data to build predictive models of biological systems that can be simulated with a computer. This allows one to disentangle molecular mechanisms from effects of shape and geometry. Questions like "what is the functional role of shape" or "how are biological shapes generated and regulated" can be addressed in the framework of image-based systems biology. The combination of image quantification, model building, and computer simulation is illustrated here using the example of diffusion in the endoplasmic reticulum.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.