Evidence map›Paper›PMID 23533143›Full record

ArticleMicroscopy research and technique2013

Quantitative zonal differentiation of articular cartilage by microscopic magnetic resonance imaging, polarized light microscopy, and Fourier-transform infrared imaging.

Ji Hyun Lee, Yang Xia

Abstract read
In one paragraph

Article in Microscopy research and technique, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Characteristics of distal femoral articular cartilage in 6 weeks posttraumatic osteoarthritis by a subcritical impact.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
  5. Article
  6. Review
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  11. Quantitative µMRI and PLM study of rabbit humeral and femoral head cartilage at sub-10 µm resolutions.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ji Hyun LeeDepartment of Physics and Center for Biomedical Research, Oakland University, Rochester, Michigan 48309, USA.
Yang Xia

Funding

Quantitative molecular imaging in articular cartilageR01AR045172 · NIAMS · OAKLAND UNIVERSITY · PI XIA, YANG · 1999 to 2009
$2.6M
Adaptability of Articular Cartilage to External Loading by Microscopic ImagingR01AR052353 · NIAMS · OAKLAND UNIVERSITY · PI XIA, YANG · 2008 to 2013
$2.1M
NIAMS NIH HHS AR045172NIAMS NIH HHS AR052353NIAMS NIH HHS R01 AR045172NIAMS NIH HHS R01 AR052353
6 · The paper itself

Abstract

This study aimed to synchronize the zonal differentiation of the full-thickness articular cartilage by three micro-imaging techniques, namely microscopic magnetic resonance imaging (µMRI), polarized light microscopy (PLM), and Fourier-transform infrared imaging (FTIRI). Eighteen cartilage-bone blocks from three canine humeral joints were imaged by: (a) µMRI T2 relaxation at 0° and 55° orientations in a 7 T magnetic field, (b) PLM optical retardation and azimuthal angle, and (c) FTIRI amide I and amide II anisotropies at 0° and 90° polarizations relative to the articular surface. In addition, µMRI T1 relaxation was imaged before and after the tissue being immersed in gadolinium (contrast agent) solution, to calculate the proteoglycan concentration. A set of previously established criteria in cartilage imaging was revised. The new criteria could simultaneously correlate the thicknesses of the three consecutive subtissue zones in articular cartilage among these imaging techniques.

Indexed as

AnimalsCartilage, ArticularDogsMagnetic Resonance ImagingMicroscopy, PolarizationSpectroscopy, Fourier Transform Infrared

Identifiers

PMID23533143
PMCPMC6350250

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.