Evidence map›Paper›PMID 23532864›Full record

ArticleAngewandte Chemie (International ed. in English)2013

High-throughput screening for terpene-synthase-cyclization activity and directed evolution of a terpene synthase.

Ryan Lauchli, Kersten S Rabe, Karolina Z Kalbarczyk, Amulya Tata, Thomas Heel, Rebekah Z Kitto, Frances H Arnold

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Optimization of IspSApplied and environmental microbiology · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
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  14. Review
  15. Review
  16. Article
  17. Article
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  19. Article
  20. Substrate specificity of α-humulene synthase fromEngineering in life sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan LauchliDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Kersten S Rabe
Karolina Z Kalbarczyk
Amulya Tata
Thomas Heel
Rebekah Z Kitto
Frances H Arnold

Funding

Chemo-enzymatic Approach to Late-stage Aromatic Fluorination of Drug ScaffoldsF32GM095061 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI LAUCHLI, RYAN MARK · 2010 to 2012
$159k
Austrian Science Fund FWF J 3327NIGMS NIH HHS F32 GM095061NIGMS NIH HHS F32GM095061
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Directed Molecular EvolutionHigh-Throughput Screening AssaysAlkyl and Aryl TransferasesCatalysisCyclizationMethanolMolecular StructureMutationSubstrate SpecificityTerpenesVinyl CompoundsAlkyl and Aryl TransferasesMethanolTerpenesterpene synthaseVinyl Compoundsvinyl ether

Identifiers

PMID23532864
PMCPMC3828198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.