ArticlePlant signaling & behavior2013
The emerging function of IQD proteins as scaffolds in cellular signaling and trafficking.
Article in Plant signaling & behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 65 citations in OpenAlex.
- The multidimensional regulation roles and mechanisms of calcium in fruit quality.Journal of integrative plant biology · 2026Review
- Splicing regulation by RS2Z36 controls ovary patterning and fruit growth in tomato.Plant molecular biology · 2026Article
- A CaPlants (Basel, Switzerland) · 2026Article
- Structure, evolution, phylogeny, and analysis of domain-deficient genes in the IQD gene family of Brassica juncea.Scientific reports · 2026Article
- E69K mutation in β-tubulin 2 blocks cell wall integrity signaling during plant cell elongation.EMBO reports · 2025Article
- Unraveling the Hormonal and Molecular Mechanisms Shaping Fruit Morphology in Plants.Plants (Basel, Switzerland) · 2025Review
- Genome-Wide Characterization of IQD Family Proteins in Apple and Functional Analysis of the Microtubule-Regulating Abilities of MdIQD17 and MdIQD28 under Cold Stress.Plants (Basel, Switzerland) · 2024Article
- Functional Analysis of thePlants (Basel, Switzerland) · 2024Article
- Morphological, histological and transcriptomic mechanisms underlying different fruit shapes inPeerJ · 2024Article
- Microtubule-associated protein SlMAP70 interacts with IQ67-domain protein SlIQD21a to regulate fruit shape in tomato.The Plant cell · 2023Article
- The cotton protein GhIQD21 interacts with GhCaM7 and modulates organ morphogenesis in Arabidopsis by influencing microtubule stability.Plant cell reports · 2023Article
- Integrative analysis of grapevine (Frontiers in nutrition · 2023Article
- Identification of the Wheat (Triticum aestivum) IQD Gene Family and an Expression Analysis of Candidate Genes Associated with Seed Dormancy and GerminationInternational journal of molecular sciences · 2022Article
- Genome-wide identification, expression analysis and evolutionary relationships of the IQ67-domain gene family in common wheat (Triticum aestivum L.) and its progenitors.BMC genomics · 2022Article
- Genome-wide analysis of IQD proteins and ectopic expression of watermelon ClIQD24 in tomato suggests its important role in regulating fruit shape.Frontiers in genetics · 2022Article
- Fruit shape lociFrontiers in plant science · 2022Article
- IQD1 Involvement in Hormonal Signaling and General Defense Responses AgainstFrontiers in plant science · 2022Article
- Article
- Genome-Wide Identification and Characterization of the PotatoFrontiers in genetics · 2021Article
- Genome-Wide Identification and Characterization of Calcium Metabolism Related Gene Families inFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium (Ca(2+)) signaling modules are essential for adjusting plant growth and performance to environmental constraints. Differential interactions between sensors of Ca(2+) dynamics and their molecular targets are at the center of the transduction process. Calmodulin (CaM) and CaM-like (CML) proteins are principal Ca(2+)-sensors in plants that govern the activities of numerous downstream proteins with regulatory properties. The families of IQ67-Domain (IQD) proteins are a large class of plant-specific CaM/CML-targets (e.g., 33 members in A. thaliana) which share a unique domain of multiple varied CaM retention motifs in tandem orientation. Genetic studies in Arabidopsis and tomato revealed first roles for IQD proteins related to basal defense response and plant development. Molecular, biochemical and histochemical analysis of Arabidopsis IQD1 demonstrated association with microtubules as well as targeting to the cell nucleus and nucleolus. In vivo binding to CaM and kinesin light chain-related protein-1 (KLCR1) suggests a Ca(2+)-regulated scaffolding function of IQD1 in kinesin motor-dependent transport of multiprotein complexes. Furthermore, because IQD1 interacts in vitro with single-stranded nucleic acids, the prospect arises that IQD1 and other IQD family members facilitate cellular RNA localization as one mechanism to control and fine-tune gene expression and protein sorting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.