Trial reportJournal of cardiothoracic surgery2013
Blood transfusion in cardiac surgery is a risk factor for increased hospital length of stay in adult patients.
Trial report in Journal of cardiothoracic surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01021631 (Transfusion Requirements After Cardiac Surgery), which is not on this map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transfusion Requirements After Cardiac Surgery: a Randomized Controlled Clinical Trial (TRACS STUDY)
Who cites it
28 citing papers in PubMed.
- Reduced risk of perioperative blood transfusions in coronary surgery: A nationwide study over 18 years.Journal of cardiothoracic surgery · 2025Article
- A comprehensive analysis of transfusion trends and patient outcomes in blood utilization practices at Jimma university medical center.Scientific reports · 2025Article
- Predictive role of cardiopulmonary bypass exposure indexed to body surface area on postoperative organ dysfunction: a retrospective cohort study.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Anemia, red blood cell transfusion and administration of blood products in obstetrics: a nationwide analysis of more than 6 million cases from 2011-2020.Blood transfusion = Trasfusione del sangue · 2024Article
- Causal determinants of postoperative length of stay in cardiac surgery using causal graphical learning.The Journal of thoracic and cardiovascular surgery · 2023Article
- Rate of Intraoperative Crystalloid Administration During Thoracic Surgery Is Causal in Reducing Postoperative Hospital Length of Stay.Ochsner journal · 2023Article
- Preoperative patient factors associated with blood product use in cardiac surgery, a retrospective cohort study.Journal of cardiothoracic surgery · 2022Article
- Investigating the association between blood transfusion and clinical outcomes in patients with acute coronary syndromes: a data linkage approach to Patient Blood Management.Blood transfusion = Trasfusione del sangue · 2022Observational
- Evaluation of Plasma Fibrinogen Levels before and after Coronary Artery Bypass Graft Surgery and Its Association with the Need for Blood Products.Advanced biomedical research · 2022Article
- Are Type and Screen Samples Routinely Necessary Before Laparoscopic Cholecystectomy?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Predictors of Length of Stay in Intensive Care Unit after Coronary Artery Bypass Grafting: Development a Risk Scoring System.Brazilian journal of cardiovascular surgery · 2021Article
- Did blood transfusion increase mortality in patients with diabetes undergoing isolated coronary artery bypass graft surgery? A propensity score-matched analysis of 816 patients.Turk gogus kalp damar cerrahisi dergisi · 2020Article
- Incidence, Risk Factors, and Nomogram of Transfusion and Associated Complications in Nonfracture Patients following Total Hip Arthroplasty.BioMed research international · 2020Article
- Article
- RBC Transfusion Strategies in the ICU: A Concise Review.Critical care medicine · 2019Review
- Impact of blood transfusion on major infection after isolated coronary artery bypass surgery: Incidence and risk factors.Journal of the Saudi Heart Association · 2019Article
- Application techniques of a novel hemostat in cardiac operations: HEMOBLAST.Journal of cardiac surgery · 2019Article
- Adverse Outcomes of Perioperative Red Blood Cell Transfusions in Coronary Artery Bypass Grafting in Hospital Universiti Sains Malaysia.The Malaysian journal of medical sciences : MJMS · 2019Article
- Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis.Annals of translational medicine · 2018Article
- Analysis of length of hospital stay using electronic health records: A statistical and data mining approach.PloS one · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAllogeneic red blood cell (RBC) transfusion has been proposed as a negative indicator of quality in cardiac surgery. Hospital length of stay (LOS) may be a surrogate of poor outcome in transfused patients.
methodsData from 502 patients included in Transfusion Requirements After Cardiac Surgery (TRACS) study were analyzed to assess the relationship between RBC transfusion and hospital LOS in patients undergoing cardiac surgery and enrolled in the TRACS study.
resultsAccording to the status of RBC transfusion, patients were categorized into the following three groups: 1) 199 patients (40%) who did not receive RBC, 2) 241 patients (48%) who received 3 RBC units or fewer (low transfusion requirement group), and 3) 62 patients (12%) who received more than 3 RBC units (high transfusion requirement group). In a multivariable Cox proportional hazards model, the following factors were predictive of a prolonged hospital length of stay: age higher than 65 years, EuroSCORE, valvular surgery, combined procedure, LVEF lower than 40% and RBC transfusion of > 3 units.
conclusionRBC transfusion is an independent risk factor for increased LOS in patients undergoing cardiac surgery. This finding highlights the adequacy of a restrictive transfusion therapy in patients undergoing cardiac surgery.
trial registrationClinicaltrials.gov identifier: http://NCT01021631.
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