Evidence map›Paper›PMID 23531179›Full record

ReviewLymphatic research and biology2013

Aged lymphatic contractility: recent answers and new questions.

Anatoliy A Gashev, Victor Chatterjee

Open access · greenAbstract readReview
In one paragraph

Review in Lymphatic research and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  8. Reply.Journal of vascular surgery cases and innovative techniques · 2021
    Article
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  14. Aged Lymphatic Vessels and Mast Cells in Perilymphatic Tissues.International journal of molecular sciences · 2017
    Review
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anatoliy A GashevDepartment of Medical Physiology, College of Medicine, Texas A&M Health Science Center, Temple, Texas 76504, USA. gashev@tamu.edu
Victor Chatterjee
Texas A&M Health Science Center · US

Funding

Lymphatic Fluid Flow Modeling with Active Network ComponentsR01HL094269 · NHLBI · TEXAS ENGINEERING EXPERIMENT STATION · PI KAUNAS, ROLAND RAYMOND · 2009 to 2012
$2.7M
Mechanisms of the Age-related Alterations in Lymphatic PumpingR01AG030578 · NIA · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI GASHEV, ANATOLIY A · 2008 to 2012
$1.5M
NHLBI NIH HHS HL-094269NIA NIH HHS R01 AG-030578
6 · The paper itself

Abstract

Abstract An overview is presented of recent findings related to biology of aging of the lymph transport system. The authors discuss recently obtained data on the aging-associated alterations of lymphatic contractility in thoracic duct and mesenteric lymphatic vessels; on comparisons of function of aged mesenteric lymphatic vessels in situ versus isolated specimens and important conclusions which arose from these studies; on aging-associated changes in functional status of mast cells located close to aged mesenteric lymphatic vessels; on evidence of presence of oxidative stress in aged lymphatic vessels and changes in arrangement of muscle cells in their walls. The authors conclude that future continuation of the research efforts in this area is necessary and will be able to provide not only novel fundamental knowledge on the biology of lymphatic aging, but also will create solid foundation for the subsequent developments of lymphatic-oriented therapeutic interventions in many diseases of the elderly.

Indexed as

Age FactorsAgingAnimalsHumansLymphatic SystemMast CellsMesenteryMuscle ContractionMuscle, SmoothThoracic Duct

Identifiers

PMID23531179
PMCPMC3609635
OpenAlexW1995650879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.