ReviewAnnals of the New York Academy of Sciences2013
Motor primitives and synergies in the spinal cord and after injury--the current state of play.
Review in Annals of the New York Academy of Sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Explaining human motor coordination via the synergy expansion hypothesis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Embodied Cooperation to Promote Forgiving Interactions With Autonomous Machines.Frontiers in neurorobotics · 2021Article
- Fuzziness of muscle synergies in patients with multiple sclerosis indicates increased robustness of motor control during walking.Scientific reports · 2020Article
- Muscular Activity Modulation During Post-operative Walking With Hybrid Assistive Limb (HAL) in a Patient With Thoracic Myelopathy Due to Ossification of Posterior Longitudinal Ligament: A Case Report.Frontiers in neurology · 2020Article
- Motor primitives are determined in early development and are then robustly conserved into adulthood.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Spinal control of muscle synergies for adult mammalian locomotion.The Journal of physiology · 2019Article
- Curated Model Development Using NEUROiD: A Web-Based NEUROmotor Integration and Design Platform.Frontiers in neuroinformatics · 2019Article
- Modular Control of Human Movement During Running: An Open Access Data Set.Frontiers in physiology · 2018Article
- On neuromechanical approaches for the study of biological and robotic grasp and manipulation.Journal of neuroengineering and rehabilitation · 2017Review
- Article
- Modular organization of the multipartite central pattern generator for turtle rostral scratch: knee-related interneurons during deletions.Journal of neurophysiology · 2016Article
- Strategy of arm movement control is determined by minimization of neural effort for joint coordination.Experimental brain research · 2016Review
- Suboptimal Muscle Synergy Activation Patterns Generalize their Motor Function across Postures.Frontiers in computational neuroscience · 2016Article
- Genetically identified spinal interneurons integrating tactile afferents for motor control.Journal of neurophysiology · 2015Review
- Somatosensory feedback refines the perception of hand shape with respect to external constraints.Neuroscience · 2015Article
- Trunk robot rehabilitation training with active stepping reorganizes and enriches trunk motor cortex representations in spinal transected rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Neuromechanical principles underlying movement modularity and their implications for rehabilitation.Neuron · 2015Review
- Human spinal locomotor control is based on flexibly organized burst generators.Brain : a journal of neurology · 2015Article
- Advancing brain-machine interfaces: moving beyond linear state space models.Frontiers in systems neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Modular pattern generator elements, also known as burst synergies or motor primitives, have become a useful and important way of describing motor behavior, albeit controversial. It is suggested that these synergy elements may constitute part of the pattern-shaping layers of a McCrea/Rybak two-layer pattern generator, as well as being used in other ways in the spinal cord. The data supporting modular synergies range across species including humans and encompass motor pattern analyses and neural recordings. Recently, synergy persistence and changes following clinical trauma have been presented. These new data underscore the importance of understanding the modular structure of motor behaviors and the underlying circuitry to best provide principled therapies and to understand phenomena reported in the clinic. We discuss the evidence and different viewpoints on modularity, the neural underpinnings identified thus far, and possible critical issues for the future of this area.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.