ReviewThe Journal of organic chemistry2013
Overcoming resistance to β-lactam antibiotics.
Review in The Journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed.
- Machine learning-based quantitative structure-activity relationship model for antibiotic prediction and discovery.PLOS digital health · 2026Article
- Prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated from animals in Bangladesh: A systematic review and meta-analysis.One health (Amsterdam, Netherlands) · 2025Review
- Article
- Exogenous adenosine counteracts tigecycline resistance inMicrobiology spectrum · 2025Article
- Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus.Bioorganic & medicinal chemistry letters · 2025Article
- NaHCO3 modulates the bla operon and β-lactam susceptibility in borderline oxacillin-resistant Staphylococcus aureus (BORSA).The Journal of antimicrobial chemotherapy · 2025Article
- The EUCAST Disk Diffusion Method for Antimicrobial Susceptibility Testing of Oral Anaerobes.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
- Prevalence, Characterization, and Proteomic Relatedness Among β-Lactam-Resistant Bacteria Throughout the Poultry Production Chain in Greece.Foods (Basel, Switzerland) · 2025Article
- Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria.Journal of oral microbiology · 2025Article
- The effect of novel β-lactam derivatives synthesized from substituted phenethylamines on resistance genes of MRSA isolates.The Journal of antibiotics · 2024Article
- Synergistic potential of LeuBMC microbiology · 2024Article
- Innovative approaches in phenotypic beta-lactamase detection for personalised infection management.Nature communications · 2024Review
- Antimicrobial Resistance Elements in Coastal Water of Llanquihue Lake, Chile.Antibiotics (Basel, Switzerland) · 2024Article
- Article
- Prevalence of Extended-Spectrum β-Lactamases (ESBLs) ProducingMicroorganisms · 2024Article
- Kinship analysis ofVeterinary world · 2024Article
- Metagenomics insights into bacterial diversity and antibiotic resistome of the sewage in the city of Belém, Pará, Brazil.Frontiers in microbiology · 2024Article
- Prevalence of diverse antimicrobial resistance genes and bacteria in sewage treatment plant-derived sludge environment.FEMS microbes · 2024Article
- Multimodal learning in clinical proteomics: enhancing antimicrobial resistance prediction models with chemical information.Bioinformatics (Oxford, England) · 2023Article
- Two-Dose Ceftiofur Treatment Increases Cephamycinase Gene Quantities and Fecal Microbiome Diversity in Dairy Cows Diagnosed with Metritis.Microorganisms · 2023Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
β-Lactam antibiotics are one of the most important antibiotic classes but are plagued by problems of resistance, and the development of new β-lactam antibiotics through side-chain modification of existing β-lactam classes is not keeping pace with resistance development. In this JOCSynopsis, we summarize small molecule strategies to overcome resistance to β-lactam antibiotics. These approaches include the development of β-lactamase inhibitors and compounds that interfere with the ability of the bacteria to sense an antibiotic threat and activate their resistance mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.