Evidence map›Paper›PMID 23529932›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2013

High-purity prostate circulating tumor cell isolation by a polymer nanofiber-embedded microchip for whole exome sequencing.

Libo Zhao, Yi-Tsung Lu, Fuqiang Li, Kui Wu, Shuang Hou, Juehua Yu, Qinglin Shen, Dongxia Wu, Min Song, Wei-Han OuYang and 10 more

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Libo ZhaoKey Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Science, Beiyi Street 2#, Zhongguancun, Beijing, 100190, P. R. China; Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging (CIMI), California NanoSystems Institute (CNSI), University of California at Los Angeles, 570 Westwood Plaza, Build 114, Los Angeles, California 90095-1770, USA.
Yi-Tsung Lu
Fuqiang Li
Kui Wu
Shuang Hou
Juehua Yu
Qinglin Shen
Dongxia Wu
Min Song
Wei-Han OuYang
Zheng Luo
Tom Lee
Xiaohong Fang
Chen Shao
Xun Xu
Mitch A Garcia
Leland W K Chung
Matthew Rettig
Hsian-Rong Tseng
Edwin M Posadas

Funding

Molecular and Functional Analysis of Single Circulating Melanoma CellsR33CA174562 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TSENG, HSIAN-RONG · 2013 to 2015
$987k
Advanced Development of An Integrated CTC Enrichment TechnologyR33CA157396 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TSENG, HSIAN-RONG · 2011 to 2013
$672k
3D-Nanostrcutured Substrates for Detection of Circulating Tumor CellsR21CA151159 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TSENG, HSIAN-RONG · 2010 to 2011
$362k
NCI NIH HHS R21 CA151159NCI NIH HHS R33 CA157396NCI NIH HHS R33 CA174562
6 · The paper itself

Abstract

Handpick single cancer cells: a modified NanoVelcro Chip is coupled with ArcturusXT laser capture microdissection (LCM) technology to enable the detection and isolation of single circulating tumor cells (CTCs) from patients with prostate cancer (PC). This new approach paves the way for conducting next-generation sequencing (NGS) on single CTCs.

Indexed as

NanofibersSequence Analysis, DNACell Line, TumorCell SeparationExomeGenomicsHumansLactic AcidMaleMicrochip Analytical ProceduresNeoplastic Cells, CirculatingPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerProstatic NeoplasmsLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymercirculating tumor cellelectrospun nanomaterialsmicrofluidicsprostate cancerwhole exome sequencing

Identifiers

PMID23529932
PMCPMC3875622

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.