ArticleAntimicrobial agents and chemotherapy2013
The animal food supplement sepiolite promotes a direct horizontal transfer of antibiotic resistance plasmids between bacterial species.
Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Environmental fate of antibiotic resistance genes in livestock farming.Archives of microbiology · 2025Review
- Competition Between Protein and DNA for Binding to Natural Sepiolite Nanofibers.International journal of nanomedicine · 2025Article
- The Effect of Saponite Clay on Ruminal Fermentation Parameters during In Vitro Studies.Animals : an open access journal from MDPI · 2024Article
- Article
- A Brief Review of Plant Cell Transfection, Gene Transcript Expression, and Genotypic Integration for Enhancing Compound Production.Methods in molecular biology (Clifton, N.J.) · 2023Review
- Mechanism for Reducing the Horizontal Transfer Risk of the Airborne Antibiotic-Resistant Genes ofInternational journal of environmental research and public health · 2022Article
- Rumen Fermentation of Feed Mixtures Supplemented with Clay Minerals in a Semicontinuous In Vitro System.Animals : an open access journal from MDPI · 2022Article
- Evolutionary Pathways and Trajectories in Antibiotic Resistance.Clinical microbiology reviews · 2021Article
- Article
- Antibiotic Resistance: Moving From Individual Health Norms to Social Norms in One Health and Global Health.Frontiers in microbiology · 2020Review
- Physico-Chemical Properties of Clay Minerals and Their Use as a Health Promoting Feed Additive.Animals : an open access journal from MDPI · 2019Review
- Clay-induced DNA breaks as a path for genetic diversity, antibiotic resistance, and asbestos carcinogenesis.Scientific reports · 2018Article
- Horizontal Plasmid Transfer by Transformation inFrontiers in microbiology · 2018Review
- Manipulating Bacterial Communities by in situ Microbiome Engineering.Trends in genetics : TIG · 2016Review
- Use of antibiotics as feed additives: a burning question.Frontiers in microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal fodder is routinely complemented with antibiotics together with other food supplements to improve growth. For instance, sepiolite is currently used as a dietary coadjuvant in animal feed, as it increases animal growth parameters and improves meat and derived final product quality. This type of food additive has so far been considered innocuous for the development and spread of antibiotic resistance. In this study, we demonstrate that sepiolite promotes the direct horizontal transfer of antibiotic resistance plasmids between bacterial species. The conditions needed for plasmid transfer (sepiolite and friction forces) occur in the digestive tracts of farm animals, which routinely receive sepiolite as a food additive. Furthermore, this effect may be aggravated by the use of antibiotics supplied as growth promoters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.