ReviewParasitology research2013
Current drug targets for helminthic diseases.
Review in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 60 citations in OpenAlex.
- Structure-guided screening of FAR-1 antagonists with multi-stage anthelmintic activity.Antimicrobial agents and chemotherapy · 2026Article
- Pesticide, Veterinary Medicines, and Microplastics: Bipartite and Tripartite Interactions Drive the Transformation of Albendazole and Pyraclostrobin in Agricultural Soils.Journal of agricultural and food chemistry · 2025Article
- Unveiling Drimenol: A Phytochemical with Multifaceted Bioactivities.Plants (Basel, Switzerland) · 2024Review
- Enhancing encapsulation of filarial antigenADMET & DMPK · 2024Article
- Natural Perylenequinone Compounds as Potent Inhibitors ofLife (Basel, Switzerland) · 2023Article
- Drug efficacy on zoonotic nematodes of the Anisakidae family: new metabolic data.Parasitology · 2022Article
- Natural Products Are a Promising Source for Anthelmintic Drug Discovery.Biomolecules · 2021Review
- Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?Frontiers in pharmacology · 2021Review
- Chemical composition and broad-spectrum anthelmintic activity of a cultivar of toothache plant,Pharmaceutical biology · 2020Article
- Article
- Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics.Scientific reports · 2019Article
- Genome mining offers a new starting point for parasitology research.Parasitology research · 2015Review
- Partial reverse of the TCA cycle is enhanced in Taenia crassiceps experimental neurocysticercosis after in vivo treatment with anthelminthic drugs.Parasitology research · 2014Article
- Molecular characterization of voltage-gated calcium channel β-subunits of Clonorchis sinensis.Parasitology research · 2014Article
- Activity of tea tree (Melaleuca alternifolia) essential oil against L3 larvae of Anisakis simplex.BioMed research international · 2014Article
- In vitro and in vivo screening of anthelmintic activity of ginger and curcumin on Ascaridia galli.Parasitology research · 2013Article
- Molecular characterization and evaluation of Onchocerca volvulus-secreted larval acidic protein 1 (SLAP1) as a putative vaccine candidate on endemic population of lymphatic filariasis.Parasitology research · 2013Article
- PGP expression in Cooperia oncophora before and after ivermectin selection.Parasitology research · 2013Article
- Molecular characterization of an rsmD-like rRNA methyltransferase from the Wolbachia endosymbiont of Brugia malayi and antifilarial activity of specific inhibitors of the enzyme.Antimicrobial agents and chemotherapy · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 2 billion people are infected with helminth parasites across the globe. The burgeoning drug resistance against current anthelmintics in parasitic worms of humans and livestock requires urgent attention to tackle these recalcitrant worms. This review focuses on the advancements made in the area of helminth drug target discovery especially from the last few couple of decades. It highlights various approaches made in this field and enlists the potential drug targets currently being pursued to target economically important helminth species both from human as well as livestock to combat disease pathology of schistosomiasis, onchocerciasis, lymphatic filariasis, and other important macroparasitic diseases. Research in the helminths study is trending to identify potential and druggable targets through genomic, proteomic, biochemical, biophysical, in vitro experiments, and in vivo experiments in animal models. The availability of major helminths genome sequences and the subsequent availability of genome-scale functional datasets through in silico search and prioritization are expected to guide the experimental work necessary for target-based drug discovery. Organized and documented list of drug targets from various helminths of economic importance have been systematically covered in this review for further exploring their use and applications, which can give physicians and veterinarians effective drugs in hand to enable them control worm infections.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.