Evidence map›Paper›PMID 23528257›Full record

ArticleNucleus (Austin, Tex.)

Jumping over the fence: RNA nuclear export revisited.

Caterina Strambio-De-Castilla

Abstract read
In one paragraph

Article in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Caterina Strambio-De-CastillaProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA. caterina.strambio@umassmed.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nuclear envelope forms a cocoon that surrounds the cellular genome keeping it out of harm's way and can be utilized by the cell as a means of functionally regulating chromatin structure and gene expression. At the same time, this double-layered membrane system constitutes a formidable obstacle to the unimpeded flow of genetic information between the genome and the rest of the cell. The nuclear pore has been long considered the sole passageway between nucleus and cytoplasm. A new report challenges this view and proposes a novel mechanism by which RNA transcripts destined for localized translation in highly polarized cell types, cross both inner and outer nuclear envelope membranes and reach the cytoplasm without utilizing the nuclear pore route.

Indexed as

CytoplasmNuclear EnvelopeActive Transport, Cell NucleusCell NucleusCell PolarityChromatinGene Expression RegulationGenomeHumansNuclear PoreNuclear ProteinsRNARNA TransportWnt Signaling PathwayChromatinNuclear ProteinsRNAneuromuscular junctionsnuclear envelopenuclear laminanuclear pore complexRNA exportWnt signaling

Identifiers

PMID23528257
PMCPMC3621751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.