ArticleBiophysical journal2013
Conformational states of melittin at a bilayer interface.
Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 63 citations in OpenAlex.
- The Role of Flexibility in the Bioactivity of Short α-Helical Antimicrobial Peptides.Antibiotics (Basel, Switzerland) · 2025Review
- Melittin can permeabilize membranes via large transient pores.Nature communications · 2024Article
- Untangling the complexity of membrane protein folding.Current opinion in structural biology · 2022Review
- Tracking Membrane Protein Dynamics in Real Time.The Journal of membrane biology · 2021Review
- Letter to the Editor: Distanced Inspiration from the Career of Stephen H. White.The Journal of membrane biology · 2021Article
- Pan-Drug ResistantAntibiotics (Basel, Switzerland) · 2020Article
- Synergistic Effects of Melittin and Plasma Treatment: A Promising Approach for Cancer Therapy.Cancers · 2019Article
- Mechanistic Landscape of Membrane-Permeabilizing Peptides.Chemical reviews · 2019Review
- How Melittin Inserts into Cell Membrane: Conformational Changes, Inter-Peptide Cooperation, and Disturbance on the Membrane.Molecules (Basel, Switzerland) · 2019Review
- The importance of the membrane interface as the reference state for membrane protein stability.Biochimica et biophysica acta. Biomembranes · 2018Article
- PackMem: A Versatile Tool to Compute and Visualize Interfacial Packing Defects in Lipid Bilayers.Biophysical journal · 2018Article
- Folding a viral peptide in different membrane environments: pathway and sampling analyses.Journal of biological physics · 2018Article
- Article
- Antimicrobial Activity of Bee Venom and Melittin against Borrelia burgdorferi.Antibiotics (Basel, Switzerland) · 2017Article
- A New Mixed All-Atom/Coarse-Grained Model: Application to Melittin Aggregation in Aqueous Solution.Journal of chemical theory and computation · 2017Article
- Computational studies of peptide-induced membrane pore formation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide.Nature communications · 2016Article
- Hydrogen Exchange Mass Spectrometry of Proteins at Langmuir Monolayers.Analytical chemistry · 2015Article
- Insights from Micro-second Atomistic Simulations of Melittin in Thin Lipid Bilayers.The Journal of membrane biology · 2015Article
- The structure of a melittin-stabilized pore.Biophysical journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
The distribution of peptide conformations in the membrane interface is central to partitioning energetics. Molecular-dynamics simulations enable characterization of in-membrane structural dynamics. Here, we describe melittin partitioning into dioleoylphosphatidylcholine lipids using CHARMM and OPLS force fields. Although the OPLS simulation failed to reproduce experimental results, the CHARMM simulation reported was consistent with experiments. The CHARMM simulation showed melittin to be represented by a narrow distribution of folding states in the membrane interface.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.