Evidence map›Paper›PMID 23528003›Full record

ArticleJournal of the American Geriatrics Society2013

Sex differences in barriers to antihypertensive medication adherence: findings from the cohort study of medication adherence among older adults.

Elizabeth Holt, Cara Joyce, Adriana Dornelles, Donald Morisky, Larry S Webber, Paul Muntner, Marie Krousel-Wood

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Pooled it
  6. Gender Differences in Cardiac Organ Damage in Arterial Hypertension: Assessing the Role of Drug Nonadherence.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
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  15. Medical Measures in Hypertensives Considered Resistant.American journal of hypertension · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth HoltCenter for Health Research, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.
Cara Joyce
Adriana Dornelles
Donald Morisky
Larry S Webber
Paul Muntner
Marie Krousel-Wood

Funding

Cohort Study of Medication Adherence Among Older AdultsR01AG022536 · NIA · OCHSNER CLINIC FOUNDATION · PI KROUSEL-WOOD, MARIE · 2005 to 2009
$2.4M
NIA NIH HHS R01 AG022536
6 · The paper itself

Abstract

objectivesTo determine whether sociodemographic, clinical, healthcare system, psychosocial, and behavioral factors are differentially associated with low antihypertensive medication adherence scores in older men and women.

designCross-sectional analysis of baseline data.

settingCohort Study of Medication Adherence in Older Adults (N = 2,194). MEASUREMENTS: Low antihypertensive medication adherence was defined as a score less than 6 on the 8-item Morisky Medication Adherence Scale. Information on risk factors for low adherence was collected using telephone surveys and administrative databases.

resultsThe prevalence of low medication adherence scores did not differ according to sex (women, 15.0%; men 13.1%; P = .21). In sex-specific multivariable models, having problems with medication cost and practicing fewer lifestyle modifications for blood pressure control were associated with low adherence scores in men and women. Factors associated with low adherence scores in men but not women were poor sexual functioning (odds ratio (OR) = 2.03, 95% confidence interval (CI) = 1.31-3.16 for men and OR = 1.28, 95% CI = 0.90-1.82 for women), and body mass index of 25.0 kg/m(2) or more (OR = 3.23, 95% CI = 1.59-6.59 for men; OR = 1.23, 95% CI = 0.82-1.85 for women). Factors associated with low adherence scores in women but not men included dissatisfaction with communication with their healthcare provider (OR = 1.75, 95% CI = 1.16-2.65 for women; OR = 1.16, 95% CI = 0.57-2.34 for men) and depressive symptoms (OR = 2.29, 95% CI = 1.55-3.38 for women; OR = 0.93, 95% CI = 0.48-1.80 for men).

conclusionFactors associated with low antihypertensive medication adherence scores differed according to sex. Interventions designed to improve adherence in older adults should be customized to account for the sex of the target population.

Indexed as

Drug MonitoringHealth BehaviorSelf ReportAdaptation, PsychologicalAgedAged, 80 and overAntihypertensive AgentsConfidence IntervalsCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedOdds RatioPrevalenceAntihypertensive Agents

Identifiers

PMID23528003
PMCPMC3628283

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.