Evidence map›Paper›PMID 23527905›Full record

ReviewMicrobial biotechnology2013

Microbiota and healthy ageing: observational and nutritional intervention studies.

Harald Brüssow

Open access · goldAbstract readReview
In one paragraph

Review in Microbial biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. The Effect of Multiprobiotics on Memory and Attention in Fibromyalgia: A Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2021
    Trial
  3. Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Role of Ames Dwarfism and Calorie Restriction on Gut Microbiota.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Harald BrüssowBioAnalytical Sciences, Food and Health Microbiology, Nestlé Research Center, Lausanne, Switzerland. harald.bruessow@rdls.nestle.com
Nestlé (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hundred years ago Metchnikoff associated human health and particularly healthy ageing with a specific type of gut microbiota. Classical culture methods associated a decrease in bifidobacteria and an increase in enterobacteria with ageing. Modern molecular methods blurred this simple picture and documented a substantial inter-individual variability for the gut microbiome even when stratifying the elderly subjects according to health status. Nutritional interventions with resistant starch showed consistent gut microbiota changes across studies from different geographical areas and prebiotic supplementation induced a 10-fold increase in gut bifidobacteria. However, in the ELDERMET study, microbiota changes do not precede, but follow the changes in health status of elderly subjects possibly as a consequence of diet changes.

Indexed as

MicrobiotaAgingDietGastrointestinal TractHumans

Identifiers

PMID23527905
PMCPMC3917467
OpenAlexW1876232886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.