ArticlePloS one2013
High-frequency TRNS reduces BOLD activity during visuomotor learning.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- The differential effect of low- versus high-frequency random noise stimulation in the treatment of tinnitus.Experimental brain research · 2015Trial
- Restoring Vision with Noninvasive Brain Stimulation: A Narrative Review.Ophthalmology and therapy · 2025Review
- The Hidden Benefits of Noise: Low-Frequency tRNS and Dynamic Visual Noise Enhance Visual Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Transcranial electrical stimulation (TES) in human motor Optimization: Mechanisms, safety, and emerging applications.Biochemistry and biophysics reports · 2025Review
- Comparing the effect of transcranial random noise stimulation and transcranial direct current stimulation over the motor cortex on motor performance in men vs. women: a randomized controlled crossover study.Frontiers in human neuroscience · 2025Article
- Random noise stimulation in the treatment of patients with neurological disorders.Neural regeneration research · 2022Review
- Effects of Noisy Galvanic Vestibular Stimulation on the Muscle Activity and Joint Movements in Different Standing Postures Conditions.Frontiers in human neuroscience · 2022Article
- Electrophysiological aftereffects of high-frequency transcranial random noise stimulation (hf-tRNS): an EEG investigation.Experimental brain research · 2021Article
- The Effects of Transcranial Electrical Stimulation on Human Motor Functions: A Comprehensive Review of Functional Neuroimaging Studies.Frontiers in neuroscience · 2020Review
- Motor Task-Dependent Dissociated Effects of Transcranial Random Noise Stimulation in a Finger-Tapping Task Versus a Go/No-Go Task on Corticospinal Excitability and Task Performance.Frontiers in neuroscience · 2019Article
- Neuroenhancement of High-Level Cognition: Evidence for Homeostatic Constraints of Non-invasive Brain Stimulation.Journal of cognitive enhancement : towards the integration of theory and practice · 2019Article
- Studying and modifying brain function with non-invasive brain stimulation.Nature neuroscience · 2018Review
- Single-Session Anodal tDCS with Small-Size Stimulating Electrodes Over Frontoparietal Superficial Sites Does Not Affect Motor Sequence Learning.Frontiers in human neuroscience · 2017Article
- Gender Differences in Food Choice: Effects of Superior Temporal Sulcus Stimulation.Frontiers in human neuroscience · 2017Article
- Opposite effects of high- and low-frequency transcranial random noise stimulation probed with visual motion adaptation.Scientific reports · 2016Article
- Motor Sequence Learning in Healthy Older Adults Is Not Necessarily Facilitated by Transcranial Direct Current Stimulation (tDCS).Geriatrics (Basel, Switzerland) · 2016Article
- Effects of anodal transcranial direct current stimulation on visually guided learning of grip force control.Biology · 2015Article
- Modulating pathological oscillations by rhythmic non-invasive brain stimulation-a therapeutic concept?Frontiers in systems neuroscience · 2015Review
- Comparing the efficacy of excitatory transcranial stimulation methods measuring motor evoked potentials.Neural plasticity · 2014Article
- Non-invasive brain stimulation for enhancement of corticospinal excitability and motor performance.Basic and clinical neuroscience · 2013Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial direct current stimulation (tDCS) and transcranial random noise stimulation (tRNS) consist in the application of electrical current of small intensity through the scalp, able to modulate perceptual and motor learning, probably by changing brain excitability. We investigated the effects of these transcranial electrical stimulation techniques in the early and later stages of visuomotor learning, as well as associated brain activity changes using functional magnetic resonance imaging (fMRI). We applied anodal and cathodal tDCS, low-frequency and high-frequency tRNS (lf-tRNS, 0.1-100 Hz; hf-tRNS 101-640 Hz, respectively) and sham stimulation over the primary motor cortex (M1) during the first 10 minutes of a visuomotor learning paradigm and measured performance changes for 20 minutes after stimulation ceased. Functional imaging scans were acquired throughout the whole experiment. Cathodal tDCS and hf-tRNS showed a tendency to improve and lf-tRNS to hinder early learning during stimulation, an effect that remained for 20 minutes after cessation of stimulation in the late learning phase. Motor learning-related activity decreased in several regions as reported previously, however, there was no significant modulation of brain activity by tDCS. In opposition to this, hf-tRNS was associated with reduced motor task-related-activity bilaterally in the frontal cortex and precuneous, probably due to interaction with ongoing neuronal oscillations. This result highlights the potential of lf-tRNS and hf-tRNS to differentially modulate visuomotor learning and advances our knowledge on neuroplasticity induction approaches combined with functional imaging methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.