SynthesisPloS one2013
The quality of reports on cervical arterial dissection following cervical spinal manipulation.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- The risk associated with spinal manipulation: an overview of reviews.Systematic reviews · 2017Pooled it
- Ischemic Stroke Associated With Vertebral Artery Occlusion Following Cervical Spine Manipulation in a Young Woman With Underlying Vascular Risk Factors: A Case Report.Clinical case reports · 2026Article
- Recurrent basilar artery thrombectomy for pediatric vertebral dissection: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Review
- A retrospective analysis of the incidence of severe adverse events among recipients of chiropractic spinal manipulative therapy.Scientific reports · 2023Article
- Letter to the Editor: A Case of Posterior Inferior Cerebellar Artery Infarction after Cervical Chiropractic Manipulation (Korean journal of neurotrauma · 2019Article
- A risk-benefit assessment strategy to exclude cervical artery dissection in spinal manual-therapy: a comprehensive review.Annals of medicine · 2019Article
- The potential dangers of neck manipulation & risk for dissection and devastating stroke: An illustrative case & review of the literature.Biomedical research and reviews · 2018Article
- Adverse events following cervical manipulative therapy: consensus on classification among Dutch medical specialists, manual therapists, and patients.The Journal of manual & manipulative therapy · 2017Article
- Cerebral Hemorrhage following Chiropractic Activator Treatment: Case Report and Review of Literature.Journal of neurological surgery reports · 2017Article
- Issues with vertebral artery dissections.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017Article
- What are the risks of manual treatment of the spine? A scoping review for clinicians.Chiropractic & manual therapies · 2017Article
- Spinal rehabilitative exercise or manual treatment for the prevention of cervicogenic headache in adults.The Cochrane database of systematic reviews · 2016Article
- Systematic Review and Meta-analysis of Chiropractic Care and Cervical Artery Dissection: No Evidence for Causation.Cureus · 2016Article
- Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes.Chiropractic & manual therapies · 2016Article
- Endovascular Treatment of Basilar Artery Thrombosis Secondary to Bilateral Vertebral Artery Dissection with Symptom Onset Following Cervical Spine Manipulation Therapy.The American journal of case reports · 2015Article
- Chiropractic Response to a Spontaneous Vertebral Artery Dissection.Journal of chiropractic medicine · 2015Article
- Correction: The Quality of Reports on Cervical Arterial Dissection following Cervical Spinal Manipulation.PloS one · 2015Article
- Presentation of an 85-year-old woman with musculoskeletal pain to a chiropractic clinic: a case of ischemic stroke.Journal of chiropractic medicine · 2014Article
- Compensation claims for chiropractic in Denmark and Norway 2004-2012.Chiropractic & manual therapies · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundCervical artery dissection (CAD) and stroke are serious harms that are sometimes associated with cervical spinal manipulation therapy (cSMT). Because of the relative rarity of these adverse events, studying them prospectively is challenging. As a result, systematic review of reports describing these events offers an important opportunity to better understand the relation between adverse events and cSMT. Of note, the quality of the case report literature in this area has not yet been assessed. PURPOSE: 1) To systematically collect and synthesize available reports of CAD that have been associated with cSMT in the literature and 2) assess the quality of these reports.
methodsA systematic review of the literature was conducted using several databases. All clinical study designs involving CADs associated with cSMT were eligible for inclusion. Included studies were screened by two independent reviewers for the presence/absence of 11 factors considered to be important in understanding the relation between CAD and cSMT.
resultsOverall, 43 articles reported 901 cases of CAD and 707 incidents of stroke reported to be associated with cSMT. The most common type of stroke reported was ischemic stroke (92%). Time-to-onset of symptoms was reported most frequently (95%). No single case included all 11 factors.
conclusionsThis study has demonstrated that the literature infrequently reports useful data toward understanding the association between cSMT, CADs and stroke. Improving the quality, completeness, and consistency of reporting adverse events may improve our understanding of this important relation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.