ArticlePloS one2013
The molecular characterization of bovine leukaemia virus isolates from Eastern Europe and Siberia and its impact on phylogeny.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34 citing papers in PubMed, 87 citations in OpenAlex.
- Genetic Diversity of the BLVPathogens (Basel, Switzerland) · 2026Article
- First Evidence of Bovine Leukemia Virus in Culicoides Biting Midges and the Stable Fly Stomoxys calcitrans Collected on Cattle Farms in Poland.Transboundary and emerging diseases · 2026Article
- Molecular epidemiology of bovine leukemia virus in cattle and phylogenetic analysis for determining its prevailing genotype in Khyber Pukhtunkhwa, Pakistan.Animal biotechnology · 2025Article
- Development and application of a quantitative polymerase chain reaction assay for the detection and genotyping of bovine leukemia virus in cattle from Kazakhstan.Veterinary world · 2025Article
- The Prevalence and Molecular Characterization of Bovine Leukemia Virus among Dairy Cattle in Henan Province, China.Viruses · 2024Article
- Inter-laboratory comparison of eleven quantitative or digital PCR assays for detection of proviral bovine leukemia virus in blood samples.BMC veterinary research · 2024Article
- Genetic Variability of Bovine Leukemia Virus: Evidence of Dual Infection, Recombination and Quasi-Species.Pathogens (Basel, Switzerland) · 2024Article
- Phylogenetic analysis of the partial sequences of theVirusdisease · 2023Article
- Design and Synthesis of Bovine Leukemia Virus-Associated Peptide-Based Qβ Conjugate Eliciting Long-Lasting Neutralizing Antibodies in Mice.ACS infectious diseases · 2022Article
- Molecular Characterization of Bovine Leukemia Virus with the Evidence of a New Genotype Circulating in Cattle from Kazakhstan.Pathogens (Basel, Switzerland) · 2022Article
- Review
- Molecular Characterization of thePathogens (Basel, Switzerland) · 2021Article
- Genotypes diversity of env gene of Bovine leukemia virus in Western Siberia.BMC genetics · 2020Article
- Effects of Naturally Occurring Mutations in Bovine Leukemia Virus 5'-LTR and Tax Gene on Viral Transcriptional Activity.Pathogens (Basel, Switzerland) · 2020Article
- Article
- New evidence of bovine leukemia virus circulating in Myanmar cattle through epidemiological and molecular characterization.PloS one · 2020Article
- Molecular characterization of bovine leukemia virus reveals existence of genotype 4 in Chinese dairy cattle.Virology journal · 2019Article
- Broadly applicable PCR restriction fragment length polymorphism method for genotyping bovine leukemia virus.The Journal of veterinary medical science · 2019Article
- Genotyping bovine leukemia virus in dairy cattle of Heilongjiang, northeastern China.BMC veterinary research · 2019Article
- Baculovirus Expression and Potential Diagnostic Application of the Gp51 Envelope Glycoprotein of Genetic Mutants of the Bovine Leukaemia Virus.Journal of veterinary research · 2019Article
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have shown that bovine leukemia virus (BLV) sequences can be classified into seven distinct genotypes based on full gp51 sequence. This classification was based on available sequence data that mainly represented the BLV population that is circulating in cattle from the US and South America. In order to aid with a global perspective inclusion of data from Eastern Europe is required. In this study we examined 44 BLV isolates from different geographical regions of Poland, Belarus, Ukraine, and Russia. Phylogenetic analysis based on a 444bp fragment of env gene revealed that most of isolates belonged to genotypes 4 and 7. Furthermore, we confirmed the existence of a new genotype, genotype 8, which was highly supported by phylogenetic computations. A significant number of amino acid substitutions were found in the sequences of the studied Eastern European isolates, of which 71% have not been described previously. The substitutions encompassed mainly the C-part of the CD4+ epitope, zinc binding peptide region, CD8+ T cell epitope, and overlapping linear epitope E. These observations highlight the use of sequence data to both elucidate phylogenetic relationships and the potential effect on serological detection of geographically diverse isolates.
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