Evidence map›Paper›PMID 23526367›Full record

ArticleAmerican journal of physical anthropology2013

Indian Ocean crossroads: human genetic origin and population structure in the Maldives.

Jeroen Pijpe, Alex de Voogt, Mannis van Oven, Peter Henneman, Kristiaan J van der Gaag, Manfred Kayser, Peter de Knijff

Open access · bronzeAbstract readHistorical Article
In one paragraph

Article in American journal of physical anthropology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jeroen PijpeDepartment of Human Genetics, Leiden University Medical Center, Postzone S5, 2300 RC Leiden, The Netherlands. knijff@lumc.nl
Alex de Voogt
Mannis van Oven
Peter Henneman
Kristiaan J van der Gaag
Manfred Kayser
Peter de Knijff
Leiden University Medical Center · NLErasmus MC · NLAmerican Museum of Natural History · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Maldives are an 850 km-long string of atolls located centrally in the northern Indian Ocean basin. Because of this geographic situation, the present-day Maldivian population has potential for uncovering genetic signatures of historic migration events in the region. We therefore studied autosomal DNA-, mitochondrial DNA-, and Y-chromosomal DNA markers in a representative sample of 141 unrelated Maldivians, with 119 from six major settlements. We found a total of 63 different mtDNA haplotypes that could be allocated to 29 mtDNA haplogroups, mostly within the M, R, and U clades. We found 66 different Y-STR haplotypes in 10 Y-chromosome haplogroups, predominantly H1, J2, L, R1a1a, and R2. Parental admixture analysis for mtDNA- and Y-haplogroup data indicates a strong genetic link between the Maldive Islands and mainland South Asia, and excludes significant gene flow from Southeast Asia. Paternal admixture from West Asia is detected, but cannot be distinguished from admixture from South Asia. Maternal admixture from West Asia is excluded. Within the Maldives, we find a subtle genetic substructure in all marker systems that is not directly related to geographic distance or linguistic dialect. We found reduced Y-STR diversity and reduced male-mediated gene flow between atolls, suggesting independent male founder effects for each atoll. Detected reduced female-mediated gene flow between atolls confirms a Maldives-specific history of matrilocality. In conclusion, our new genetic data agree with the commonly reported Maldivian ancestry in South Asia, but furthermore suggest multiple, independent immigration events and asymmetrical migration of females and males across the archipelago.

Indexed as

Gene FlowAsian PeopleChromosomes, Human, YDNA, MitochondrialFemaleGenetic MarkersGenetics, PopulationHaplotypesHistory, AncientHuman MigrationHumansIndian Ocean IslandsMalePolymorphism, Single NucleotideDNA, MitochondrialGenetic Markers

Identifiers

PMID23526367
PMCPMC3652038
OpenAlexW1761972356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.