ArticleApplied mathematics letters2013
Quantifying CFSE Label Decay in Flow Cytometry Data.
Article in Applied mathematics letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Shining a light on fluorescent EV dyes: Evaluating efficacy, specificity and suitability by nano-flow cytometry.Journal of extracellular biology · 2024Article
- Article
- Storage-Induced Micro-Erythrocytes Can Be Quantified and Sorted by Flow Cytometry.Frontiers in physiology · 2022Article
- Detection and Sorting of Extracellular Vesicles and Viruses Using nanoFACS.Current protocols in cytometry · 2020Article
- Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division.Journal of mathematical biology · 2014Article
- Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis.Frontiers in immunology · 2013Review
- A novel statistical analysis and interpretation of flow cytometry data.Journal of biological dynamics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We developed a series of models for the label decay in cell proliferation assays when the intracellular dye carboxyfluorescein succinimidyl ester (CFSE) is used as a staining agent. Data collected from two healthy patients were used to validate the models and to compare the models with the Akiake Information Criteria. The distinguishing features of multiple decay rates in the data are readily characterized and explained via time dependent decay models such as the logistic and Gompertz models.
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Registered trials
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