SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2013
A systematic review of repeat hepatectomy for recurrent colorectal liver metastases.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study.British journal of cancer · 2016Trial
- Current status of minimally invasive liver surgery for cancers.World journal of gastroenterology · 2022Review
- Limited Effect of Perioperative Systemic Therapy in Patients Selected for Repeat Local Treatment of Recurrent Colorectal Cancer Liver Metastases.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Current treatment and surveillance modalities are not sufficient for advanced stage III colon cancer: Result from a multicenter cohort analysis.Cancer medicine · 2021Article
- Liver Transplantation for Colorectal Liver Metastases: Current Management and Future Perspectives.International journal of molecular sciences · 2021Review
- Recurrence After Liver Resection of Colorectal Liver Metastases: Repeat Resection or Ablation Followed by Hepatic Arterial Infusion Pump Chemotherapy.Annals of surgical oncology · 2021Article
- THE ERA OF MANAGEMENT OF COLORECTAL LIVER METASTASES.The Ulster medical journal · 2020Article
- Article
- A postoperative scoring system for post-hepatectomy early recurrence of colorectal liver metastases.Oncotarget · 2017Article
- Surgical salvage of recurrence after resection of colorectal liver metastases: incidence and outcomes.Hepatic oncology · 2017Article
- Surveillance after curative treatment for colorectal cancer.Nature reviews. Clinical oncology · 2017Review
- Repeat hepatectomy is independently associated with favorable long-term outcome in patients with colorectal liver metastases.Cancer medicine · 2017Article
- Postoperative complications following aggressive repeat hepatectomy for colorectal liver metastasis have adverse oncological outcomes.Surgery today · 2017Article
- Posttreatment Surveillance in Patients with Prolonged Disease-Free Survival After Resection of Colorectal Liver Metastasis.Annals of surgical oncology · 2016Article
- Liver regeneration following repeat SBRT.Journal of gastrointestinal oncology · 2015Article
- Unresolved issues and controversies surrounding the management of colorectal cancer liver metastasis.World journal of surgical oncology · 2015Review
- Maximum Diameter and Number of Tumors as a New Prognostic Indicator of Colorectal Liver Metastases.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSelected patients with recurrent colorectal liver metastases (CLM) may be resectable by repeat hepatectomy approach. In this review, we aim to collate and evaluate the published evidence for repeat hepatectomy in patients with recurrent CLM.
methodsSearches of the Medline and Embase databases were undertaken to identify studies of repeat hepatectomy in patients with recurrent CLM focusing on the perioperative treatment regimen, operative strategy, morbidity, technical success and survival outcomes.
resultsTwenty-two observational studies were reviewed. A total of 1,610 patients underwent second hepatectomy for recurrent CLM. The median percentage of extra-hepatic disease was 15 % (range, 0-39 %). Preoperative chemotherapy was reported in 5/22 studies. Major liver resection was undertaken in 25 % (range, 9-59 %) of patients and the R0 resection rate was 90 % (range, 77-96 %). Postoperative morbidity and mortality after the second hepatectomy were 23 % and 1.2 %, respectively. Recurrence rate after second hepatectomy was 63.9 % (range, 42-91 %) with a median follow-up period of 32 months (range, 19-59 months). Median overall survival was 35 months (range, 19-56 months). The 3-year and 5-year overall survival rates were 55 % (range, 11-82 %) and 42 % (range, 31-73 %), respectively.
conclusionSecond hepatectomy is safe and feasible in selected patients with recurrent CLM and is associated with acceptable perioperative and survival outcomes. Future prospective studies are required to further define the patient selection criteria for repeat hepatectomy and the exact role of perioperative chemotherapy.
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