Evidence map›Paper›PMID 23525549›Full record

ArticleInternational orthopaedics2013

Evaluation of sonicate fluid cultures in comparison to histological analysis of the periprosthetic membrane for the detection of periprosthetic joint infection.

Viktor Janz, Georgi I Wassilew, Olaf Hasart, Georg Matziolis, Stephan Tohtz, Carsten Perka

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in International orthopaedics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 6 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 6 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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  15. Sonication of removed implants improves microbiological diagnosis of postoperative spinal infections.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Article
  16. Culturing periprosthetic tissue in blood culture bottles results in isolation of additional microorganisms.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
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  19. Evaluation of the use of sonication of retrieved implants for the diagnosis of prosthetic joint infection in a routine setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Viktor JanzOrthopaedic Department, Center for Musculoskeletal Surgery, Charité - Universitätsmedizin, Charitéplatz 1, 10117, Berlin, Germany. Viktor.Janz@Charite.de
Georgi I Wassilew
Olaf Hasart
Georg Matziolis
Stephan Tohtz
Carsten Perka
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this prospective study was to evaluate the diagnostic efficacy of sonicate fluid cultures (SFC) and the histological analysis of the periprosthetic membrane (PM) for the detection of periprosthetic joint infection (PJI).

methodsThe histological samples were evaluated according to the consensus classification of PM as defined by Morawietz and Krenn. All explanted endoprosthesis were subject to sonication. Additionally, a synovial aspiration and microbiological culture of tissue samples were performed for each patient. Twenty three of the 59 patients had an established PJI.

resultsSonication achieved the highest sensitivity out of all diagnostic methods with 91 % and a specificity of 81 %. The PM achieved a sensitivity of 87 % and a specificity of 100 %. In three cases of PJI a pathogen was isolated solely by sonication while all other microbiological methods were negative. In seven cases there was a positive bacterial culture through sonication with negative histology.

conclusionsOur results show a high correlation between the microbiological and histological results. In our patient group sonication achieved the highest sensitivity out of all diagnostic methods and was more sensitive than conventional microbiological methods.

Indexed as

AgedBacteriaBacterial InfectionsBacteriological TechniquesBiopsy, NeedleFemaleHumansJoint ProsthesisJointsMaleProsthesis FailureProsthesis-Related InfectionsSensitivity and SpecificitySonicationSynovial Membrane

Identifiers

PMID23525549
PMCPMC3631497
OpenAlexW2064782226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.