Evidence map›Paper›PMID 23525348›Full record

ArticleFrontiers in pharmacology2013

Eosinophil recruitment and activation: the role of lipid mediators.

Tatiana Luna-Gomes, Patrícia T Bozza, Christianne Bandeira-Melo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. Systemic and metabolic control of liver regeneration.Trends in endocrinology and metabolism: TEM · 2026
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  8. Parasitic infections: A new frontier for PGDCurrent research in immunology · 2024
    Review
  9. Review
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  11. Review
  12. Review
  13. Exosomes: A Key Piece in Asthmatic Inflammation.International journal of molecular sciences · 2021
    Review
  14. Leptin ElicitsFrontiers in endocrinology · 2020
    Article
  15. Article
  16. Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating TFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  17. Article
  18. FABP4 regulates eosinophil recruitment and activation in allergic airway inflammation.American journal of physiology. Lung cellular and molecular physiology · 2018
    Article
  19. Decoding the chemotactic signal.Journal of leukocyte biology · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Tatiana Luna-GomesInstituto de Biofïsica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil.
Patrícia T Bozza
Christianne Bandeira-Melo
Fundação Oswaldo Cruz · BRInstituto de Biofísica Carlos Chagas FilhoUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well-established and involve several steps controlled by adhesion molecules, priming agents, chemotactic, and surviving factors. Even though the majority of studies focused on role of protein mediators like IL-5 and eotaxins, lipid mediators also participate in eosinophil recruitment and activation. Among the lipid mediators with distinguish eosinophil recruitment and activation capabilities are platelet activating factor and the eicosanoids, including leukotriene B4, cysteinyl leukotrienes, and prostaglandin D2. In this review, we focused on the role of these four lipid mediators in eosinophil recruitment and activation, since they are recognized as key mediators of eosinophilic inflammatory responses.

Indexed as

chemotaxiseosinophilleukotrieneslipid mediatorsprostaglandins

Identifiers

PMID23525348
PMCPMC3605515
OpenAlexW2004482801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.