Evidence map›Paper›PMID 23524947›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2013

Sex, weight status, and chronic kidney disease among African Americans: the Jackson Heart Study.

Marino A Bruce, Bettina M Beech, Errol D Crook, Mario Sims, Derek M Griffith, Sean L Simpson, Jamy Ard, Keith C Norris

Open access · greenAbstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Stress and the kidney.Advances in chronic kidney disease · 2015
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Marino A BruceMississippi Institute for the Improvement of Geographic Minority Health, University of Mississippi Medical Center, Jackson, MS 39216, USA. mbruce@umc.edu
Bettina M Beech
Errol D Crook
Mario Sims
Derek M Griffith
Sean L Simpson
Jamy Ard
Keith C Norris
University of Mississippi Medical Center · USWake Forest University · USCharles R. Drew University of Medicine and Science · USJackson State University · USUniversity of South Alabama · USVanderbilt University · US

Funding

YQ MICRODELETIONS AND MALE INFERTILITYP20RR011145 · NCRR · CHARLES R. DREW UNIVERSITY OF MED &SCI · PI NORRIS, KEITH C · 1995 to 2009
$17.0M
TRAINING COREP20MD000182 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED &SCI · PI BROWN, ARLEEN F., MARTINS, DAVID SANE · 2002 to 2016
$16.5M
Vanderbilt Center for Diabetes Translation ResearchP30DK092986 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ELASY, TOM A · 2011 to 2020
$6.7M
Statistical Methods for Whole-Brain Connectivety NetworksK25EB012236 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SIMPSON, SEAN L · 2012 to 2016
$796k
Disparities in CHD in the Jackson Heart StudyK01HL084682 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI SIMS, MARIO · 2006 to 2010
$634k
Socio-economic Distress and Chronic Kidney Disease in the Jackson Heart StudyK01HL088735 · NHLBI · MEHARRY MEDICAL COLLEGE · PI BRUCE, MARINO A · 2007 to 2011
$627k
NCRR NIH HHS P20 RR011145NHLBI NIH HHS 1 K01 HL084682-01NHLBI NIH HHS 1 K01 HL88735-05NHLBI NIH HHS K01 HL084682NHLBI NIH HHS K01 HL088735NIBIB NIH HHS K25 EB012236NIDDK NIH HHS P30 DK092986NIMHD NIH HHS P20 MD000182
6 · The paper itself

Abstract

backgroundObesity has been shown to have implications for chronic kidney disease (CKD); however, it has received minimal attention from scientists studying CKD among African Americans.

objectivesThe purpose of this study was to examine the manner in which weight status has implications for CKD among this group through analysis of data drawn from the Jackson Heart Study (JHS).

designCross-sectional analysis of a single-site longitudinal population-based cohort.

participantsThe data for this study were drawn from the baseline examination of the Jackson Heart Study (JHS). The analytic cohort consisted of 3430 African American men and women (21-84 years of age) living in the tricounty area of the Jackson, Mississippi metropolitan areas with complete data to determine CKD status. MAIN MEASUREMENTS: The primary dependent variable was CKD (defined as the presence of albuminuria or reduced estimated glomerular filtration rate <60 mL/min per 1.73 m(2)). Weight status, the primary predictor, was a 4-category measure based on body mass index.

resultsAssociations were explored through bivariable analyses and multivariable logistic regression analyses adjusting for CKD, weight status, diabetes, hypertension, and cardiovascular disease risk factors as well as demographic factors. The prevalence of CKD in the JHS was 20%. The proportion of overweight, class I, and class II obese individuals was 32.5%, 26.9%, and 26.2% respectively. In the pooled model, weight status was not found to be associated with CKD; however, subgroup analysis revealed that class II obesity was associated with CKD among men (odds ratio, 2.37; confidence interval, 1.34-4.19) but not among women (odds ratio, 1.32; confidence interval, 0.88-1.98). The relationship between CKD prevalence and diabetes and CKD prevalence and hypertension varied by sex and differed across weight categories.

conclusionsWeight status has implications for CKD among the JHS participants, and this study underscores the need for additional research investigating the relationship between weight status, sex, and CKD among African Americans.

Indexed as

Body WeightAdultAgedAged, 80 and overBlack or African AmericanBody Mass IndexCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedMississippiObesityOdds RatioRenal Insufficiency, Chronic

Identifiers

PMID23524947
PMCPMC4862367
OpenAlexW71741592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.