Evidence map›Paper›PMID 23524684›Full record

ArticleOncoimmunology2013

Macrophages: Good guys in colorectal cancer.

Sofia Edin, Maria L Wikberg, Per-Arne Oldenborg, Richard Palmqvist

Abstract read
In one paragraph

Article in Oncoimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. The prognostic index of mScientific reports · 2022
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Macrophage Polarization States in the Tumor Microenvironment.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Engineering MacrophagesFrontiers in oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia EdinDepartment of Medical Biosciences, Pathology; Umeå University; Umeå, Sweden.
Maria L Wikberg
Per-Arne Oldenborg
Richard Palmqvist

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages play a complex role in tumor progression since they can exert both tumor-preventing (M1 macrophages) and tumor-promoting (M2 macrophages) activities. In colorectal carcinoma (CRC), at odds to many other cancers, macrophage infiltration has been correlated with an improved patient survival. In a recent study, we have evaluated the distribution of M1 and M2 macrophage subtypes in CRC and their impact on patient prognosis.

Indexed as

colorectal cancerCpG island methylator phenotypemacrophage subtypesmicrosatellite instabilityprognosis

Identifiers

PMID23524684
PMCPMC3601174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.