ArticleJournal of chemical neuroanatomy2013
Differential expression of vesicular glutamate transporters 1 and 2 may identify distinct modes of glutamatergic transmission in the macaque visual system.
Article in Journal of chemical neuroanatomy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 59 citations in OpenAlex.
- A conserved pulvinar projection to the amygdala revealed in macaque monkeys (Macaca mulatta).Brain structure & function · 2026Article
- Circadian rhythms of neuronal and astrocytic glutamate transporters in the suprachiasmatic nucleus of mice.Frontiers in cellular neuroscience · 2026Article
- Article
- Characterizing Evoked Movement Patterns and Connectivity in Sensorimotor Cortex After Sensory Loss in Squirrel Monkeys.The Journal of comparative neurology · 2025Article
- Article
- Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus.Frontiers in neuroanatomy · 2025Article
- Functional Connectivity Favors Aberrant Visual Network c-Fos Expression Accompanied by Cortical Synapse Loss in a Mouse Model of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Article
- Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their 'readout' of visual input.Nature neuroscience · 2023Article
- Retinorecipient areas in the common marmoset (Frontiers in neural circuits · 2023Review
- Thalamocortical and corticothalamic connections of multiple functional domains in posterior parietal cortex of galagos.The Journal of comparative neurology · 2023Article
- Immunoelectron Microscopic Characterization of Vasopressin-Producing Neurons in the Hypothalamo-Pituitary Axis of Non-Human Primates by Use of Formaldehyde-Fixed Tissues Stored at -25 °C for Several Years.International journal of molecular sciences · 2021Article
- Cortical connections of the functional domain for climbing or running in posterior parietal cortex of galagos.The Journal of comparative neurology · 2021Article
- Immunoreactivity of Vesicular Glutamate Transporter 2 Corresponds to Cytochrome Oxidase-Rich Subcompartments in the Visual Cortex of Squirrel Monkeys.Frontiers in neuroanatomy · 2021Article
- The postnatal development of MT, V1, LGN, pulvinar and SC in prosimian galagos (Otolemur garnettii).The Journal of comparative neurology · 2020Article
- VGluT1 Deficiency Impairs Visual Attention and Reduces the Dynamic Range of Short-Term Plasticity at Corticothalamic Synapses.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Organization of primate amygdalar-thalamic pathways for emotions.PLoS biology · 2020Article
- The Evolution of the Pulvinar Complex in Primates and Its Role in the Dorsal and Ventral Streams of Cortical Processing.Vision (Basel, Switzerland) · 2019Review
- Diverse glutamatergic inputs target spines expressing M1 muscarinic receptors in the basolateral amygdala: An ultrastructural analysis.Brain research · 2019Article
- The sensory thalamus and visual midbrain in mouse lemurs.The Journal of comparative neurology · 2019Article
- Architectonic features and relative locations of primary sensory and related areas of neocortex in mouse lemurs.The Journal of comparative neurology · 2019Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Glutamate is the primary neurotransmitter utilized by the mammalian visual system for excitatory neurotransmission. The sequestration of glutamate into synaptic vesicles, and the subsequent transport of filled vesicles to the presynaptic terminal membrane, is regulated by a family of proteins known as vesicular glutamate transporters (VGLUTs). Two VGLUT proteins, VGLUT1 and VGLUT2, characterize distinct sets of glutamatergic projections between visual structures in rodents and prosimian primates, yet little is known about their distributions in the visual system of anthropoid primates. We have examined the mRNA and protein expression patterns of VGLUT1 and VGLUT2 in the visual system of macaque monkeys, an Old World anthropoid primate, in order to determine their relative distributions in the superior colliculus, lateral geniculate nucleus, pulvinar complex, V1 and V2. Distinct expression patterns for both VGLUT1 and VGLUT2 identified architectonic boundaries in all structures, as well as anatomical subdivisions of the superior colliculus, pulvinar complex, and V1. These results suggest that VGLUT1 and VGLUT2 clearly identify regions of glutamatergic input in visual structures, and may identify common architectonic features of visual areas and nuclei across the primate radiation. Additionally, we find that VGLUT1 and VGLUT2 characterize distinct subsets of glutamatergic projections in the macaque visual system; VGLUT2 predominates in driving or feedforward projections from lower order to higher order visual structures while VGLUT1 predominates in modulatory or feedback projections from higher order to lower order visual structures. The distribution of these two proteins suggests that VGLUT1 and VGLUT2 may identify class 1 and class 2 type glutamatergic projections within the primate visual system (Sherman and Guillery, 2006).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.