ArticleBone2013
Dancing with sex hormones, could iron contribute to the gender difference in osteoporosis?
Article in Bone, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02854722 (Phase 2 Study of Deferasirox-calcium-vitamin D3 to Treat Postmenopausal Osteoporosis), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase 2 Study of Deferasirox-calcium-vitamin D3 to Treat Postmenopausal Osteoporosis (PMOP)
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Osteoporosis and bone mineral density in patients with Wilson's disease: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Pooled it
- Association of serum ferritin with bone turnover markers and bone mineral density in children and adolescents: Finding from NHANES 1999-2002.The Journal of international medical research · 2026Article
- Sex-dependent variation in bone adaptation: from degeneration to regeneration.Journal of orthopaedic translation · 2025Review
- COPB1 deficiency triggers osteoporosis with elevated iron stores by inducing osteoblast ferroptosis.Journal of orthopaedic translation · 2025Article
- TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- The influence of iron on bone metabolism disorders.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Review
- Iron accumulation induced by hepcidin1 knockout accelerates the progression of aging osteoporosis.Journal of orthopaedic surgery and research · 2024Article
- Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition.eLife · 2023Article
- Role of Iron Accumulation in Osteoporosis and the Underlying Mechanisms.Current medical science · 2023Article
- Estrogen Up-Regulates Iron Transporters and Iron Storage Protein Through Hypoxia Inducible Factor 1 Alpha Activation Mediated by Estrogen Receptor β and G Protein Estrogen Receptor in BV2 Microglia Cells.Neurochemical research · 2022Article
- Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea.Scientific reports · 2022Article
- Deciphering core proteins of osteoporosis with iron accumulation by proteomics in human bone.Frontiers in endocrinology · 2022Article
- Iron accumulation deteriorated bone loss in estrogen-deficient rats.Journal of orthopaedic surgery and research · 2021Article
- Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson's disease.Cell death and differentiation · 2021Article
- Observational
- Review
- Despite Genetic Iron Overload,JBMR plus · 2019Article
- Post-acute Transitional Journey: Caring for Orthopedic Surgery Patients in the United States.Frontiers in medicine · 2018Article
- Reducing iron accumulation: A potential approach for the prevention and treatment of postmenopausal osteoporosis.Experimental and therapeutic medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.