ArticlePublic health nutrition2013
Pre-pregnancy obesity and maternal nutritional biomarker status during pregnancy: a factor analysis.
Article in Public health nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- The effect of prepregnancy body mass index on maternal micronutrient status: a meta-analysis.Scientific reports · 2021Pooled it
- Maternal Adiposity and DNA Methylation of TfR2 and HJV Genes in Early Pregnancy: Mediating Role of Inflammation and Consequences for Iron Status.The Journal of nutrition · 2026Trial
- Maternal obesity, fish intake, and recurrent spontaneous preterm birth.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019Trial
- Maternal Pre-Pregnancy Obesity Attenuates Response to Omega-3 Fatty Acids Supplementation During Pregnancy.Nutrients · 2018Trial
- Article
- Palmitate and group BFrontiers in immunology · 2024Article
- Fetal sex differences in placental LCPUFA ether and plasmalogen phosphatidylethanolamine and phosphatidylcholine contents in pregnancies complicated by obesity.Biology of sex differences · 2023Article
- Folate and vitamin B12 status: associations with maternal glucose and neonatal DNA methylation sites related to dysglycaemia, in pregnant women with obesity.Journal of developmental origins of health and disease · 2022Article
- Disparities in Vitamin D Status of Newborn Infants from a Diverse Sociodemographic Population in Montreal, Canada.The Journal of nutrition · 2022Article
- How the placenta-brain lipid axis impacts the nutritional origin of child neurodevelopmental disorders: Focus on attention deficit hyperactivity disorder and autism spectrum disorder.Experimental neurology · 2022Review
- Long-Chain Polyunsaturated Fatty Acid Concentrations and Association with Weight Gain in Pregnancy.Nutrients · 2021Article
- Longitudinal Plasma Metabolomics Profile in Pregnancy-A Study in an Ethnically Diverse U.S. Pregnancy Cohort.Nutrients · 2021Article
- Article
- Review
- The Influence of Obesity and Associated Fatty Acids on Placental Inflammation.Clinical therapeutics · 2021Review
- Obesity, gestational weight gain, and polyunsaturated fatty acids profile in pregnant Saudi women.Bioinformation · 2020Article
- Association between pre-pregnancy weight status and maternal micronutrient status in early pregnancy.Public health nutrition · 2018Article
- Article
- Impact of Pre-Pregnancy BMI on B Vitamin and Inflammatory Status in Early Pregnancy: An Observational Cohort Study.Nutrients · 2016Observational
- Pregnancy-Related Changes of Amino Acid and Acylcarnitine Concentrations: The Impact of Obesity.AJP reports · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivePre-pregnancy obesity has been associated with adverse birth outcomes. Poor essential fatty acid (EFA) and micronutrient status during pregnancy may contribute to these associations. We assessed the associations between pre-pregnancy BMI and nutritional patterns of maternal micronutrient and EFA status during mid-pregnancy.
designA cross-sectional analysis from a prospective cohort study. Women provided non-fasting blood samples at ≥ 20 weeks’ gestation that were assayed for red cell EFA; plasma folate, homocysteine and ascorbic acid; and serum retinol, 25-hydroxyvitamin D, a-tocopherol, soluble transferrin receptors and carotenoids. These nutritional biomarkers were employed in a factor analysis and three patterns were derived: EFA, Micronutrients and Carotenoids.
settingThe Antidepressant Use During Pregnancy Study, Pittsburgh, PA, USA. SUBJECTS: Pregnant women (n 129).
resultsAfter adjustment for parity, race/ethnicity and age, obese pregnant women were 3.0 (95% CI 1.1, 7.7) times more likely to be in the lowest tertile of the EFA pattern and 4.5 (95% CI 1.7, 12.3) times more likely to be in the lowest tertile of the Carotenoid pattern compared with their lean counterparts. We found no association between pre-pregnancy obesity and the Micronutrient pattern after confounder adjustment.
conclusionsOur results suggest that obese pregnant women have diminished EFA and carotenoid concentrations.
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Registered trials
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