Evidence map›Paper›PMID 23522622›Full record

ReviewTrends in cell biology2013

Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance.

John A Schiel, Carly Childs, Rytis Prekeris

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Exosome: an overview on enhanced biogenesis by small molecules.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. IPIP27 Coordinates PtdIns(4,5)PCurrent biology : CB · 2019
    Article
  12. Article
  13. Rab GTPases and cell division.Small GTPases · 2018
    Review
  14. Article
  15. Polarized Exocytosis.Cold Spring Harbor perspectives in biology · 2017
    Review
  16. Article
  17. Myosin-independent cytokinesis inProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

John A SchielProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Carly Childs
Rytis Prekeris
University of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · USUniversity of Massachusetts Chan Medical School · US

Funding

Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and CiliogenesisR01DK064380 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Rytis Prekeris · 2004 to 2026
$7.1M
NIDDK NIH HHS R01 DK064380
6 · The paper itself

Abstract

Abscission is the last step of cytokinesis that leads to the physical separation of two daughter cells. An emerging picture is that abscission is a complex event that relies on changes in both lipid composition and cytoskeletal dynamics. These subcellular processes lead to the establishment of the abscission site and recruitment of the ESCRT-III protein complex to mediate the final separation event. It has become apparent that endocytic transport to the cleavage furrow during late cytokinesis mediates and coordinates lipid and cytoskeleton dynamics, thus playing a key role in abscission. Furthermore, new evidence suggests that endosomes may have additional roles in post-mitotic cellular events such as midbody inheritance and degradation. Here, we highlight recent findings regarding the function of these endosomes in the regulation of cell division.

Indexed as

CytokinesisActomyosinAnimalsCell DivisionCytoskeletonEndosomal Sorting Complexes Required for TransportEndosomesHumansModels, BiologicalrhoA GTP-Binding ProteinActomyosinEndosomal Sorting Complexes Required for TransportrhoA GTP-Binding Protein

Identifiers

PMID23522622
PMCPMC4228945
OpenAlexW2099719055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.