ArticleEnvironmental research2013
Associations between ambient air pollution and Hypertensive Disorders of Pregnancy.
Article in Environmental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Prenatal PM2.5 exposure and hypertensive disorders of pregnancy: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Meta-Prediction of MTHFR Gene Polymorphisms and Air Pollution on the Risk of Hypertensive Disorders in Pregnancy Worldwide.International journal of environmental research and public health · 2018Pooled it
- Ambient Ultrafine Particles and Hypertensive Disorders of Pregnancy: A Mediation Analysis of Homocysteine in a Birth Cohort.Environment & health (Washington, D.C.) · 2026Article
- Increased Risk of Gestational Hypertension by Periconceptional Exposure to Ambient Air Pollution and Effect Modification by Prenatal Depression.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Association between particulate air pollution and hypertensive disorders in pregnancy: A retrospective cohort study.PLoS medicine · 2024Article
- Gestational ozone inhalation elicits maternal cardiac dysfunction and transcriptional changes to placental pericytes and endothelial cells.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Association of ambient PMiScience · 2023Article
- Environmental Exposure: Effect on Maternal Morbidity and Mortality and Neonatal Health.Cureus · 2023Review
- Ozone Exposure During Pregnancy and Risk of Gestational Hypertension or Preeclampsia in China.JAMA network open · 2023Article
- Risk of De Novo Hypertensive Disorders of Pregnancy After Exposure to PM1 and PM2.5 During the Period From Preconception to Delivery: Birth Cohort Study.JMIR public health and surveillance · 2023Article
- Smog and risk of maternal and fetal birth outcomes: A retrospective study in Baoding, China.Open medicine (Warsaw, Poland) · 2022Article
- Exposure to ambient air pollution during pregnancy and inflammatory biomarkers in maternal and umbilical cord blood: The Healthy Start study.Environmental research · 2021Article
- Epidemiological trends of maternal hypertensive disorders of pregnancy at the global, regional, and national levels: a population-based study.BMC pregnancy and childbirth · 2021Article
- Drinking water contaminants in California and hypertensive disorders in pregnancy.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Inflammatory effects of particulate matter air pollution.Environmental science and pollution research international · 2020Review
- Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study.BMC public health · 2020Article
- Correlation between exposure to fine particulate matter and hypertensive disorders of pregnancy in Shanghai, China.Environmental health : a global access science source · 2020Article
- Exposure to urban particulate matter and its association with human health risks.Environmental science and pollution research international · 2020Review
- Prenatal exposure to traffic and ambient air pollution and infant weight and adiposity: The Healthy Start study.Environmental research · 2020Article
- Adverse Effects of Exposure to Fine Particulate Matters and Ozone on Gestational Hypertension.Current medical science · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundExposure to ambient air pollution is linked to adverse pregnancy outcomes. Previous reports examining the relationship between ambient air pollution and Hypertensive Disorders of Pregnancy have been inconsistent.
objectivesWe evaluated the effects of ambient air pollution on the odds of Hypertensive Disorder of Pregnancy and whether these associations varied by body mass index (BMI).
methodsWe conducted a retrospective, case-control study among 298 predominantly Hispanic women (136 clinically confirmed cases) who attended the Los Angeles County+University of Southern California Women's and Children's Hospital during 1996-2008. Trimester-specific carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O3), and particulate matter with aerodynamic diameter <10 μm and <2.5 μm (PM10, PM2.5) exposure were estimated based on 24-hour exposure level at residential address. Logistic regression models were fitted to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for two standard deviation increase in exposure levels.
resultsExposures to CO and PM2.5 in the 1st trimester were significantly associated with Hypertensive Disorders of Pregnancy, and these associations were modified by BMI. In non-obese women (BMI <30), 1st trimester exposures to PM2.5 and CO were significantly associated with increased odds of Hypertensive Disorder of Pregnancy (ORs per 2-standard deviation increase in PM2.5 (7 μg/m(3)) and CO (1 ppm) exposures were 9.10 [95% CI: 3.33-24.6] and 4.96 [95% CI: 1.85-13.31], respectively). Additionally, there was a significantly positive association between exposure to O3 in the 2nd trimester and Hypertensive Disorder of Pregnancy (OR per 15 ppb=2.05; 95% CI: 1.22-3.46).
conclusionAmong non-obese women, 1st trimester exposure to PM2.5 and carbon monoxide are associated with increased odds of Hypertensive Disorder of Pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.