Evidence map›Paper›PMID 23522471›Full record

ArticleMethods in enzymology2013

Using Xenopus skin to study cilia development and function.

Michael E Werner, Brian J Mitchell

Abstract read
In one paragraph

Article in Methods in enzymology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
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  4. Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade-offs in response to changes in salinity.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
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  13. Convergence of autism proteins at the cilium.bioRxiv : the preprint server for biology · 2025
    Article
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  15. Article
  16. The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport.American journal of respiratory cell and molecular biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael E WernerDepartment of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Brian J Mitchell

Funding

Developmental Dynamics of Ciliated EpitheliaR01GM089970 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MITCHELL, BRIAN JOSEPH · 2010 to 2022
$4.4M
NIGMS NIH HHS R01 GM089970NIGMS NIH HHS R01GM089970
6 · The paper itself

Abstract

Cilia are prevalent biological structures that are important for cell signaling and for generating fluid flow (or motility). Cilia are found throughout biology from single-celled organisms to vertebrates, and many model systems have been employed for their analysis. Here, we describe the use of Xenopus larval skin as a system for the study of ciliogenesis and ciliary function. In particular, we describe basic molecular and embryological manipulations and imaging techniques that have proven particularly useful for understanding the polarized beating of cilia and the generation of directed fluid flow (Werner & Mitchell, 2012). However, these same tools have the potential to benefit a large number of cilia-related biological questions.

Indexed as

AnimalsBody PatterningCiliaSignal TransductionSkinXenopus

Identifiers

PMID23522471
PMCPMC4319646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.