ArticleLipids in health and disease2013
Associations of SAA1 gene polymorphism with lipid lelvels and osteoporosis in Chinese women.
Article in Lipids in health and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- The role of metabolites under the influence of genes and lifestyles in bone density changes.Frontiers in nutrition · 2022Article
- Relationship Between Serum Amyloid A1 (Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- LMCD1 promotes osteogenic differentiation of human bone marrow stem cells by regulating BMP signaling.Cell death & disease · 2019Article
- Article
- Circulating Serum Amyloid A, hs-CRP and Vitamin D Levels in Postmenopausal Osteoporosis.Galen medical journal · 2019Article
- Review
- Rs12218 In SAA1 gene was associated with serum lipid levels.Lipids in health and disease · 2013Article
- 4q22.1 contributes to bone mineral density and osteoporosis susceptibility in postmenopausal women of Chinese Han population.PloS one · 2013Article
- Serum amyloid a gene polymorphism and its association with lipid profile in Saudi females with osteoporosis.Pakistan journal of medical sciencesArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe development of osteoporosis is associated with several risk factors, such as genetic polymorphisms and enviromental factors. This study assessed the correlation between SAA1 gene rs12218 polymorphism and HDL-C lelvels and osteoporosis in a population of Chinese women.
methodsA total of 387 postmenopausal female patients who were diagnosed with osteoporosis (case group) based on bone mineral density measurements via dual-energy x-ray absorptiometry and 307 females with no osteoporosis (control group) were included in this study. Correlations between SAA1 gene rs12218 polymorphism and osteoporosis and HDL-C level were investigated through the identification of SAA1 gene rs12218 polymorphism genotypes using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
resultsThe TT genotype of rs12218 was more frequently in osteoporosis patients than in control subjects (P <0.001). And the rs12218 was found to be associated with plasma TG, HDL-C, LDL-C, and BMD levels in osteoporosis patients (P<0.05).
conclusionsThe present results indicate that both osteoporosis and lipids levels are associated with the TT genotype of rs12218 in the human SAA1 gene.
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