Evidence map›Paper›PMID 23522093›Full record

ArticleArchives of gerontology and geriatrics

Sleep, type 2 diabetes, dyslipidemia, and hypertension in elderly Alzheimer's caregivers.

Jennifer Schwartz, Matthew A Allison, Sonia Ancoli-Israel, Melbourne F Hovell, Ruth E Patterson, Loki Natarajan, Simon J Marshall, Igor Grant

Open access · greenAbstract read
In one paragraph

Article in Archives of gerontology and geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Association between sleep, care burden, and related factors among family caregivers at home.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jennifer SchwartzSan Diego State University/University of California, San Diego, Joint Doctoral Program in Public Health, San Diego, CA, United States. Jeschwartz@ucsd.edu
Matthew A Allison
Sonia Ancoli-Israel
Melbourne F Hovell
Ruth E Patterson
Loki Natarajan
Simon J Marshall
Igor Grant
University of California, San Diego · USSan Diego State University · US

Funding

ALZHEIMER CAREGIVER COPING--MENTAL AND PHYSICAL HEALTHR01AG015301 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 1997 to 2011
$7.6M
Alzheimer Caregiver Coping: Mental and Physical HealthRF1AG015301 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR, MAUSBACH, BRENT T · 2014 to 2014
$4.4M
SLEEP CONSOLIDATION IN A NURSING HOME POPULATIONR01AG008415 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANCOLI-ISRAEL, SONIA · 1989 to 2011
$3.0M
Transdisciplinary Training for Predoctoral Behavioral ScientistsT32GM084896 · NIGMS · SAN DIEGO STATE UNIVERSITY · PI HOVELL, MELBOURNE F · 2008 to 2012
$789k
NIA NIH HHS AG08415NIA NIH HHS AG15301NIA NIH HHS R01 AG008415NIA NIH HHS R01 AG015301NIA NIH HHS RF1 AG015301NIGMS NIH HHS T32 GM084896NIGMS NIH HHS T32GM084896
6 · The paper itself

Abstract

Research indicates that very short or long durations of sleep and inefficient sleep are associated with higher total cholesterol and risk of type 2 diabetes and hypertension. This study tested the hypothesis that inefficient sleep or short/long sleep durations are associated with an elevated prevalence of type 2 diabetes, dyslipidemia, and hypertension in a community-dwelling sample of elderly Alzheimer's caregivers. Participants were 126 caregivers for spouses with Alzheimer's disease who underwent in-home sleep assessment by wrist actigraphy for 72 consecutive hours. Sleep data were averaged across the 3 days/nights; nighttime sleep and daytime napping were computed. Morning fasting blood samples were collected to determine measures of blood lipids and glucose. The average of three resting blood pressure measurements was used to estimate mean resting blood pressure. Logistic regression models including covariates related to sleep and metabolic regulation indicated that nighttime sleep duration, percent sleep at night, and daytime naps were not significantly associated with odds of having diabetes (OR, 0.92; 95% CI, 0.56-1.53; OR, 0.93; 95% CI, 0.83-1.03; OR, 1.75; 95% CI, 0.74-4.11, respectively), dyslipidemia (OR, 0.83; 95% CI, 0.57-1.20; OR, 0.99; 95% CI, 0.92-1.07; OR, 0.64; 95% CI, 0.33-1.24, respectively), or hypertension (OR, 0.97; 95%CI, 0.62-1.52; OR, 1.02; 95% CI, 0.93-1.11; OR, 1.10; 95% CI, 0.44-2.74, respectively). When categorical and combined sleep parameters were examined, there were no significant associations with any of the metabolic conditions (all p>0.05). The current study suggests that in an elderly sample of Alzheimer's caregivers, nighttime sleep duration, nighttime sleep efficiency and daytime naps are not significantly associated with prevalent type 2 diabetes, dyslipidemia, or hypertension. As several of the associations demonstrated clinically relevant magnitudes of the associations, larger studies to more fully test these hypotheses are warranted.

Indexed as

Alzheimer DiseaseCaregiversFamily HealthAgedDiabetes Mellitus, Type 2DyslipidemiasFemaleHumansHypertensionMaleMiddle AgedSleep DeprivationStress, Psychological

Identifiers

PMID23522093
PMCPMC3696346
OpenAlexW2066864189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.