ArticlePsychological medicine2013
Cognition in schizophrenia and schizo-affective disorder: impairments that are more similar than different.
Article in Psychological medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Visual integration deficits associated with psychosis are independent of diagnosis.Schizophrenia (Heidelberg, Germany) · 2025Article
- Reduced Visual Function in Schizotypal Traits: An Exploratory Study.Schizophrenia bulletin · 2025Article
- Cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but not schizotypy.Schizophrenia research. Cognition · 2022Article
- Retrieval practice facilitation of family psychoeducation in people with early psychosis.Schizophrenia research · 2020Article
- Cognitive and clinical predictors of community functioning across the psychoses.PsyCh journal · 2020Article
- The characteristics of cognitive neuroscience tests in a schizophrenia cognition clinical trial: Psychometric properties and correlations with standard measures.Schizophrenia research. Cognition · 2020Article
- Cross-diagnostic analysis of cognitive control in mental illness: Insights from the CNTRACS consortium.Schizophrenia research · 2019Article
- The continuing story of schizophrenia and schizoaffective disorder: One condition or two?Schizophrenia research. Cognition · 2019Article
- Memory and cognition in schizophrenia.Molecular psychiatry · 2019Review
- Aripiprazole, A Drug that Displays Partial Agonism and Functional Selectivity.Current neuropharmacology · 2017Article
- Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder.Schizophrenia research. Cognition · 2017Article
- Explicit and implicit reinforcement learning across the psychosis spectrum.Journal of abnormal psychology · 2017Article
- Multiple forms of contour grouping deficits in schizophrenia: what is the role of spatial frequency?Neuropsychologia · 2014Article
- Cognitive impairments in psychotic disorders: common mechanisms and measurement.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2014Article
- Generalized and specific neurocognitive deficits in psychotic disorders: utility for evaluating pharmacological treatment effects and as intermediate phenotypes for gene discovery.Schizophrenia bulletin · 2014Review
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundCognition is increasingly being recognized as an important aspect of psychotic disorders and a key contributor to functional outcome. In the past, comparative studies have been performed in schizophrenia and schizo-affective disorder with regard to cognitive performance, but the results have been mixed and the cognitive measures used have not always assessed the cognitive deficits found to be specific to psychosis. A set of optimized cognitive paradigms designed by the Cognitive Neuroscience Test Reliability and Clinical Applications for Schizophrenia (CNTRACS) Consortium to assess deficits specific to schizophrenia was used to measure cognition in a large group of individuals with schizophrenia and schizo-affective disorder.
methodA total of 519 participants (188 with schizophrenia, 63 with schizo-affective disorder and 268 controls) were administered three cognitive paradigms assessing the domains of goal maintenance in working memory, relational encoding and retrieval in episodic memory and visual integration.
resultsAcross the three domains, the results showed no major quantitative differences between patient groups, with both groups uniformly performing worse than healthy subjects.
conclusionsThe findings of this study suggests that, with regard to deficits in cognition, considered a major aspect of psychotic disorder, schizophrenia and schizo-affective disorder do not demonstrate major significant distinctions. These results have important implications for our understanding of the nosological structure of major psychopathology, providing evidence consistent with the hypothesis that there is no natural distinction between cognitive functioning in schizophrenia and schizo-affective disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.