ArticleBipolar disorders2013
Phenomenology of bipolar disorder not otherwise specified in youth: a comparison of clinical characteristics across the spectrum of manic symptoms.
Article in Bipolar disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The morbidity of subthreshold pediatric bipolar disorder: A systematic literature review and meta-analysis.Bipolar disorders · 2019Pooled it
- Early Family Intervention for Youth at Risk for Bipolar Disorder: Psychosocial and Neural Mediators of Outcome.Current neuropharmacology · 2023Trial
- Effects of family intervention on psychosocial functioning and mood symptoms of youth at high risk for bipolar disorder.Journal of consulting and clinical psychology · 2022Trial
- Longitudinal trajectories of mood symptoms and global functioning in youth at high risk for bipolar disorder.Journal of affective disorders · 2020Trial
- Amygdala-prefrontal cortical functional connectivity during implicit emotion processing differentiates youth with bipolar spectrum from youth with externalizing disorders.Journal of affective disorders · 2017Trial
- Mediators in the randomized trial of Child- and Family-Focused Cognitive-Behavioral Therapy for pediatric bipolar disorder.Behaviour research and therapy · 2016Trial
- A Randomized Controlled Trial of Individual Family Psychoeducational Psychotherapy and Omega-3 Fatty Acids in Youth with Subsyndromal Bipolar Disorder.Journal of child and adolescent psychopharmacology · 2015Trial
- Rest-Activity Rhythms and Suicidal Ideation in Pediatric Bipolar Disorder.Bipolar disorders · 2026Article
- Comparing Youth With Bipolar Disorder to Non-Bipolar Youth Referred for Bipolar Disorder.JAACAP open · 2025Article
- Error monitoring and response inhibition in adolescents with bipolar disorders: An ERP study.Cognitive, affective & behavioral neuroscience · 2025Article
- Sleep quality predicts future mood symptoms in adolescents with bipolar disorder.Journal of affective disorders · 2024Article
- Neural abnormalities of reward processing in adolescents with bipolar disorders: An ERP study.Biological psychology · 2023Article
- Social impairment in relation to clinical symptoms in youth at high risk for bipolar disorder.Early intervention in psychiatry · 2022Article
- Prospectively ascertained mania and hypomania among young adults with child- and adolescent-onset bipolar disorder.Bipolar disorders · 2021Article
- Demographic and Clinical Characteristics, Including Subsyndromal Symptoms Across Bipolar-Spectrum Disorders in Adolescents.Journal of child and adolescent psychopharmacology · 2020Article
- Characteristics of youth at high risk for bipolar disorder compared to youth with bipolar I or II disorder.Journal of psychiatric research · 2020Article
- Neurophysiological correlates of cognitive control and approach motivation abnormalities in adolescent bipolar disorders.Cognitive, affective & behavioral neuroscience · 2019Article
- Assessment of a Person-Level Risk Calculator to Predict New-Onset Bipolar Spectrum Disorder in Youth at Familial Risk.JAMA psychiatry · 2017Article
- Characterization and structure of hypomania in a British nonclinical adolescent sample.Journal of affective disorders · 2017Article
- Toward the Definition of a Bipolar Prodrome: Dimensional Predictors of Bipolar Spectrum Disorders in At-Risk Youths.The American journal of psychiatry · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 1 country.
Funding
Abstract
objectivesControversy surrounds the diagnostic categorization of children with episodic moods that cause impairment, but do not meet DSM-IV criteria for bipolar I (BD-I) or bipolar II (BD-II) disorder. This study aimed to characterize the degree to which these children, who meet criteria for bipolar disorder not otherwise specified (BD-NOS), are similar to those with full syndromal BD, versus those with no bipolar spectrum diagnosis (no BSD).
methodsChildren aged 6-12 years were recruited from nine outpatient clinics, preferentially selected for higher scores on a 10-item screen for manic symptoms. Interviews with the children and their primary caregivers assessed a wide array of clinical variables, as well as family history.
resultsA total of 707 children [mean ± standard deviation (SD) 9.4 ± 1.9 years old] were evaluated at baseline, and were diagnosed with BD-I (n = 71), BD-II (n = 3), BD-NOS (including cyclothymia; n = 88), or no BSD (n = 545). Compared to BD-I, the BD-NOS group had less severe past functional impairment. However, current symptom severity and functional impairment did not differ between BD-NOS and BD-I, even though both groups were significantly more symptomatic and impaired than the no BSD group. Parental psychiatric history was similar for the BD-NOS and BD-I groups, and both were more likely than the no BSD group to have a parent with a history of mania. Rates of elated mood did not differ between BD-NOS and BD-I youth.
conclusionsChildren with BD-NOS and BD-I are quite similar, but different from the no BSD group, on many phenomenological measures. These findings support the hypothesis that BD-NOS is on the same spectrum as BD-I.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.