Evidence map›Paper›PMID 23520595›Full record

ReviewILAR journal2012

Advancing addiction treatment: what can we learn from animal studies?

Peter H Wu, Kalynn M Schulz

Abstract readReview
In one paragraph

Review in ILAR journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter H WuDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Research Complex-1 North, Mail Stop 8344, 12800 East 19th Avenue, Aurora, Colorado 80045, USA. peter.wu@ucdenver.edu
Kalynn M Schulz

Funding

Molecular Mechanisms of Alcohol Tolerance in Brain NeuronsR21AA018328 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI WU, PO HSIUNG · 2010 to 2011
$408k
Gender-Dependent Effects of Stress During Adolescence on Adult Brain and BehaviorIK2BX001562 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI SCHULZ, KALYNN · 2012 to 2016
–
BLRD VA IK2 BX001562NIAAA NIH HHS AA018328NIAAA NIH HHS R21 AA018328
6 · The paper itself

Abstract

Substance addiction is a maladaptive behavior characterized by compulsive and uncontrolled self-administration of a substance (drug). Years of research indicate that addictive behavior is the result of complex interactions between the drug, the user, and the environment in which the drug is used; therefore, addiction cannot simply be attributed to the neurobiological actions of a drug. However, despite the obvious complexity of addictive behavior, animal models have both advanced understanding of addiction and contributed importantly to the development of medications to treat this disease. We briefly review recent animal models used to study drug addiction and the contribution of data generated by these animal models for the clinical treatment of addictive disorders.

Indexed as

AnimalsBehavior, AddictiveHumansModels, AnimalSubstance-Related Disorders

Identifiers

PMID23520595
PMCPMC7802088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.