Trial reportThe European respiratory journal2013
Simple functional performance tests and mortality in COPD.
Trial report in The European respiratory journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 3 syntheses or guidelines pooled it, 207 citations in OpenAlex.
- Predictors of mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis.BMC pulmonary medicine · 2022Pooled it
- Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Physical exercise for people with cirrhosis.The Cochrane database of systematic reviews · 2018Pooled it
- Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.The European respiratory journal · 2026Trial
- Personalised Health Behaviour Support Programme in Adults With Post-COVID Syndrome: A Randomised, Controlled Pilot Feasibility Trial.Health expectations : an international journal of public participation in health care and health policy · 2024Trial
- "Can do, don't do" are not the lazy ones: a longitudinal study on physical functioning in patients with COPD.Respiratory research · 2020Trial
- Oral nutrition supplements and between-meal snacks for nutrition therapy in patients with COPD identified as at nutritional risk: a randomised feasibility trial.BMJ open respiratory research · 2019Trial
- Effect of counselling during pulmonary rehabilitation on self-determined motivation towards physical activity in people with chronic obstructive pulmonary disease - protocol of a mixed methods study.BMC pulmonary medicine · 2017Trial
- Trial
- Early telemedicine training and counselling after hospitalization in patients with severe chronic obstructive pulmonary disease: a feasibility study.BMC medical informatics and decision making · 2015Trial
- The one repetition maximum test and the sit-to-stand test in the assessment of a specific pulmonary rehabilitation program on peripheral muscle strength in COPD patients.International journal of chronic obstructive pulmonary disease · 2015Trial
- Associations between body mass index and peak expiratory flow rate and the mediating role of hand grip strength: evidence from CHARLS.Clinics (Sao Paulo, Brazil) · 2026Article
- A novel machine learning model of smartphone-based 1-minute sit-to-stand test for prediction of six-minute walk test distance in patients with COPD.Clinics (Sao Paulo, Brazil) · 2026Article
- Performance on the one-minute sit-to-stand test predicts long-term adverse outcomes in pulmonary hypertension.Scientific reports · 2026Article
- Impact of dynapenia, presarcopenia and sarcopenia in chronic obstructive pulmonary disease: a prospective cohort study.BMJ open respiratory research · 2025Article
- Reference values for the 1-minute sit-to-stand test to assess functional capacity and short-term mortality in people with idiopathic pulmonary fibrosis and fibrotic connective tissue related interstitial lung diseases: a prospective real-world cohort study.BMC pulmonary medicine · 2025Article
- The prevalence of small airways disease and association with handgrip strength in young Hispanic farmworkers.BMC pulmonary medicine · 2024Article
- Prevalence and prognostic importance of exercise limitation and physical inactivity in COPD.Breathe (Sheffield, England) · 2024Review
- Article
- The one-minute sit-to-stand-test performance is associated with health-related quality of life in patients with pulmonary hypertension.PloS one · 2024Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise tests are important to characterise chronic obstructive pulmonary disease patients and predict their prognosis, but are often not available outside of rehabilitation or research settings. Our aim was to assess the predictive performance of the sit-to-stand and handgrip strength tests. The prospective cohort study in Dutch and Swiss primary care settings included a broad spectrum of patients (n=409) with Global Initiative for Chronic Obstructive Lung Disease stages II to IV. To assess the association of the tests with outcomes, we used Cox proportional hazards (mortality), negative binomial (centrally adjudicated exacerbations) and mixed linear regression models (longitudinal health-related quality of life) while adjusting for age, sex and severity of disease. The sit-to-stand test was strongly (adjusted hazard ratio per five more repetitions of 0.58, 95% CI 0.40-0.85; p=0.004) and the handgrip strength test moderately strongly (0.84, 95% CI 0.72-1.00; p=0.04) associated with mortality. Both tests were also significantly associated with health-related quality of life but not with exacerbations. The sit-to-stand test alone was a stronger predictor of 2-year mortality (area under curve 0.78) than body mass index (0.52), forced expiratory volume in 1 s (0.61), dyspnoea (0.63) and handgrip strength (0.62). The sit-to-stand test may close an important gap in the evaluation of exercise capacity and prognosis of chronic obstructive pulmonary disease patients across practice settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.