A tangled threesome: adiponectin, insulin sensitivity, and adiposity: can Mendelian randomization sort out causality?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Improving Adiponectin Levels in Individuals With Diabetes and Obesity: Insights From Look AHEAD.Diabetes care · 2015
   Trial
2. The Potential Chemopreventive Effect ofInternational journal of molecular sciences · 2023
   Article
3. MLR-1023 Treatment in Mice and Humans Induces a Thermogenic Program, and Menthol Potentiates the Effect.Pharmaceuticals (Basel, Switzerland) · 2021
   Article
4. Puberty Status Modifies the Effects of Genetic Variants, Lifestyle Factors and Their Interactions on Adiponectin: The BCAMS Study.Frontiers in endocrinology · 2021
   Article
5. Anti-inflammatory and anti-proliferative action of adiponectin mediated by insulin signaling cascade in human vascular smooth muscle cells.Molecular biology reports · 2020
   Article
6. The etiology of oxidative stress in insulin resistance.Biomedical journal · 2017
   Article
7. Higher circulating adiponectin levels are associated with increased risk of atrial fibrillation in older adults.Heart (British Cardiac Society) · 2015
   Article
8. Liver function parameters in hip fracture patients: relations to age, adipokines, comorbidities and outcomes.International journal of medical sciences · 2015
   Article
9. Adiponectin, cardiovascular disease, and mortality: parsing the dual prognostic implications of a complex adipokine.Metabolism: clinical and experimental · 2014
   Article
10. Obesity, inflammation, and lung injury (OILI): the good.Mediators of inflammation · 2014
    Review
11. Adiponectin, driver or passenger on the road to insulin sensitivity?Molecular metabolism · 2013
    Review

Corrections and comments

• Comment on
  Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study.2013

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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