Evidence map›Paper›PMID 23520237›Full record

Trial reportStroke2013

Method for enhancing real-world use of a more affected arm in chronic stroke: transfer package of constraint-induced movement therapy.

Edward Taub, Gitendra Uswatte, Victor W Mark, David M Morris, Joydip Barman, Mary H Bowman, Camille Bryson, Adriana Delgado, Staci Bishop-McKay

6 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Stroke, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 79 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03114046 nacompletednot on this mapstarted 2017, after this paper: background citation

Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2017 to 2018Enrolled8ConditionsRehabilitation, Recovery of Function, Stroke, Lower Extremity ParesisArmsLower extremity Constraint-induced movement therapy(LE-CIMT)
NCT04546217 nacompletednot on this mapstarted 2020, after this paper: background citation

Gait Training Combined With Strategies to Induce Transference to Real Life for People With Stroke

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2020 to 2023Enrolled19ConditionsStroke, Gait, Hemiplegic, Behavior and Behavior MechanismsArmsTreadmill training + transfer package (TT+TP), Treadmill training (TT)
NCT05311384 nacompletednot on this mapstarted 2022, after this paper: background citation

Application of a Reimbursable Form of Constraint-Induced Movement Therapy for Upper Extremity Recovery Following Stroke: A Pilot Study

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2022 to 2024Enrolled10ConditionsCVA (Cerebrovascular Accident), Stroke, Upper Extremity ParesisArmsKeys Constraint-induced Movement Therapy protocol
NCT05492513 narecruitingnot on this mapstarted 2022, after this paper: background citation

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment and Deficits in Desired Occupational Performance: A Pilot Study

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2022 to 2027Enrolled12ConditionsCVA (Cerebrovascular Accident), Stroke, Upper Extremity ParesisArmsGrade 1 CI Therapy +Sensory Components
NCT05515237 narecruitingnot on this mapstarted 2023, after this paper: background citation

Constraint-Induced Movement Therapy Plus Sensory Components for Adults With Mild-to-Severe Arm and Hand Impairment After Stroke

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2023 to 2027Enrolled15ConditionsCVA (Cerebrovascular Accident), Stroke, Upper Extremity ParesisArmsGrade 2-5 CI Therapy + Sensory Components
NCT07710521 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparing Two Moral Injury Treatments: Acceptance and Commitment Therapy for Moral Injury and Present Centered Therapy for Moral Injury

TypeinterventionalSponsorVA Eastern Colorado Health Care SystemRan2026 to 2030Enrolled180ConditionsMoral InjuryArmsAcceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Repetitive task training for improving functional ability after stroke.The Cochrane database of systematic reviews · 2016
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edward TaubDepartment of Psychology, University of Alabama, Birmingham, CPM 712, 1530 3rd Ave, S, Birmingham, AL 35294, USA. etaub@uab.edu
Gitendra Uswatte
Victor W Mark
David M Morris
Joydip Barman
Mary H Bowman
Camille Bryson
Adriana Delgado
Staci Bishop-McKay

Funding

TREATMENT FOR EXCESS MOTOR DISABILITY IN THE AGEDR01HD034273 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TAUB, EDWARD · 1997 to 2007
$3.1M
NICHD NIH HHS HD34273NICHD NIH HHS R01 HD034273
6 · The paper itself

Abstract

background and purposeConstraint-induced movement therapy is a set of treatments for rehabilitating motor function after central nervous system damage. We assessed the roles of its 2 main components.

methodsA 2 × 2 factorial components analysis with random assignment was conducted. The 2 factors were type of training and presence/absence of a set of techniques to facilitate transfer of therapeutic gains from the laboratory to the life situation (Transfer Package; TP). Participants (N=40) were outpatients ≥ 1-year after stroke with hemiparesis. The different treatments, which in each case targeted the more affected arm, lasted 3.5 hours/d for 10 weekdays. Spontaneous use of the more affected arm in daily life and maximum motor capacity of that arm in the laboratory were assessed with the Motor Activity Log and the Wolf Motor Function Test, respectively.

resultsUse of the TP, regardless of the type of training received, resulted in Motor Activity Log gains that were 2.4 times as large as the gains in its absence (P<0.01). These clinical results parallel previously reported effects of the TP on neuroplastic change. Both the TP and training by shaping enhanced gains on the Wolf Motor Function Test (P<0.05). The Motor Activity Log gains were retained without loss 1 year after treatment. An additional substudy (N=10) showed that a single component of the TP, weekly telephone contact with participants for 1 month after treatment, doubled Motor Activity Log scores at 6-month follow-up.

conclusionsThe TP is a method for enhancing both spontaneous use of a more affected arm after chronic stroke and its maximum motor capacity. Shaping enhances the latter.

Indexed as

Stroke RehabilitationAdultAgedAged, 80 and overArmExercise TherapyFemaleHumansMaleMiddle AgedParesisRecovery of FunctionStrokeTreatment Outcome

Identifiers

PMID23520237
PMCPMC3703737

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.