ArticleClinical research in cardiology : official journal of the German Cardiac Society2013
Angiographic score assessment improves cardiovascular risk prediction: the clinical value of SYNTAX and Gensini application.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04636112 (Effects of Sleep Habits on Acute Myocardial Infarction Risk and Severity of Coronary Artery Disease in Chinese Population), which is not on this map. Cited by 92 papers.
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The trial behind it
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Effects of Sleep Habits on Acute Myocardial Infarction Risk and Severity of Coronary Artery Disease in Chinese Population
Who cites it
92 citing papers in PubMed, 182 citations in OpenAlex.
- Aggregate Clinical and Biomarker-Based Model Predicts Adverse Outcomes in Patients With Coronary Artery Disease.The American journal of cardiology · 2023Trial
- Correlation Analysis of Acute Coronary Syndrome with Serum IL-18, MMP-9, hs-CRP, and Plasma FIB.BioMed research international · 2022Trial
- Influence of the Residual Gensini Score on Prognosis of Patients With ST-Elevation Myocardial Infarction.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
- Retinol-binding Protein 4 as a Predictor of Cardiovascular Events after Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction.Journal of atherosclerosis and thrombosis · 2026Article
- HDL-C as a potential mediator between serum 25(OH)D and the angiographic severity of coronary artery disease: a single-center cross-sectional study.Clinics (Sao Paulo, Brazil) · 2026Article
- Higher Dietary Insulinemic Potential, and Triglyceride-Glucose (TyG)-BMI Index may Contribute to Coronary Artery Disease Severity: a Cross-Sectional Study.Journal of epidemiology and global health · 2025Article
- The relationship between Gensini score and rates of 30-day mortality in acute coronary syndrome patients in China.BMC cardiovascular disorders · 2025Article
- Increased dietary acid load May elevate the risk of coronary artery disease severity: Findings from a cross-sectional study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Electrocardiographic R Wave Peak Time: Correlation With the Severity of Coronary Artery Disease and Prognosis in Patients With Acute Coronary Syndrome.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- Investigating the dietary inflammatory index and pro-inflammatory immune dynamics: insights from a cross-sectional study of severe vs. non-severe coronary artery disease patients.European journal of medical research · 2025Article
- Successful or Uncomplicated Use of Drug-Coated Balloon Versus Drug-Eluting Stent Strategies for De Novo Culprit Lesions in Acute Coronary Syndromes: Insights from a Nationwide Registry in Japan.Journal of the American Heart Association · 2025Observational
- Real-Time Coronary Artery Dominance Classification from Angiographic Images Using Advanced Deep Video Architectures.Diagnostics (Basel, Switzerland) · 2025Article
- Ultra-processed foods and coronary artery disease severity: a cross-sectional study of at-risk normal-weight and overweight patients undergoing elective angiography.Journal of health, population, and nutrition · 2025Article
- Effect of Homoarginine on Coronary Artery Complexity and Atherosclerotic Burden in Patients with STEMI.Journal of clinical medicine · 2025Article
- Association of d-dimer levels with in-hospital death and multi-vessel coronary artery disease in patients with non-ST-segment elevation acute coronary syndrome.Frontiers in medicine · 2025Article
- Value of lipoprotein(a) in predicting severity of coronary artery stenosis in patients with chronic coronary artery disease: a cross-sectional study in Vietnam.Frontiers in cardiovascular medicine · 2025Article
- Risk factors for in-hospital heart failure in patients with acute myocardial infarction and construction of predictive models.American journal of translational research · 2025Article
- Relationship between uric acid to HDL ratio and extent and severity of coronary artery disease.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Chronic Total Occlusions in Non-Infarct-Related Coronary Arteries and Long-Term Cardiovascular Mortality in Patients Receiving Percutaneous Coronary Intervention in Acute Coronary Syndromes.Journal of clinical medicine · 2024Article
- The predictive value of lesion-specific pericoronary fat attenuation index for major adverse cardiovascular events in patients with type 2 diabetes.Cardiovascular diabetology · 2024Article
32 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeverity of coronary artery disease (CAD) is related to cardiovascular outcome. We aimed to assess the long-term follow-up depending on Synergy between percutaneous coronary intervention with Taxus and cardiac surgery (SYNTAX) and Gensini score for prognosis. Both scores increase with complexity and thus reflect risk of cardiovascular events. METHODS AND
resultsWe determined complexity and extent of CAD by the SYNTAX and Gensini score in the AtheroGene cohort (N = 1,974, with 22.6 % women). The endpoint was non-fatal myocardial infarction (N = 132) and cardiovascular death (N = 159) over a median follow-up of 5.4 (Q1: 5.23/Q3: 5.57) years up to 8 years maximum (follow-up rate 99.4%). For SYNTAX score, the following distribution was used: low (≤22, N = 1,404), medium (23-32, N = 314), high score (>32, N = 256). Gensini score was split into thirds. Cox regression analysis showed a hazard ratio (HR) of 1.5 (95% confidence interval 1.16-1.95; p = 0.0024) for the log transformed SYNTAX score in a fully adjusted model and a HR of 1.41 (95% CI 1.13-1.77; p = 0.0025) for the Gensini score. The SYNTAX score alone had a C-index of 0.62, whereas adding clinical variables increased the C-index to 0.67. Similar results were obtained for the Gensini score. Regarding the SYNTAX score using net reclassification index, discrimination of events and non-events was enhanced by 37.2% in a model of clinical variables and biomarkers and by 31.8% for the Gensini score.
conclusionThe SYNTAX and Gensini score in combination with clinical variables could be used to predict the cardiovascular prognosis during a long-term follow-up of up to 8 years in CAD patients.
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