Evidence map›Paper›PMID 23519525›Full record

ArticleHeart and vessels2014

Clinical significance of heart rate during acute decompensated heart failure to predict left ventricular reverse remodeling and prognosis in response to therapies in nonischemic dilated cardiomyopathy.

Shunsuke Ishii, Takayuki Inomata, Yuki Ikeda, Takeru Nabeta, Miwa Iwamoto, Ichiro Watanabe, Takashi Naruke, Hisahito Shinagawa, Toshimi Koitabashi, Mototsugu Nishii and 2 more

Abstract read
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Article in Heart and vessels, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Hemodynamic, management, and outcomes of patients admitted to emergency department with heart failure.Scandinavian journal of trauma, resuscitation and emergency medicine · 2016
    Article
  8. Article
  9. Observational
  10. Article
  11. Observational
  12. Article
  13. Effect of Ginkgo biloba extract on experimental cardiac remodeling.BMC complementary and alternative medicine · 2015
    Article
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shunsuke IshiiDepartment of Cardio-Angiology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan, sishii@med.kitasato-u.ac.jp.
Takayuki Inomata
Yuki Ikeda
Takeru Nabeta
Miwa Iwamoto
Ichiro Watanabe
Takashi Naruke
Hisahito Shinagawa
Toshimi Koitabashi
Mototsugu Nishii
Ichiro Takeuchi
Tohru Izumi
Kitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although an increased heart rate (HR) is a strong predictor of poor prognosis in cases of chronic heart failure (HF), the clinical value of HR as a predictor in acute decompensated HF (ADHF) is unclear. Seventy-eight patients with nonischemic dilated cardiomyopathy (NIDCM) with sinus rhythm who were first hospitalized for ADHF from 2002 to 2010 were retrospectively investigated after exclusion of patients with tachycardia-induced cardiomyopathy. The patients were divided into two groups stratified by HR on admission with a median value of 113 beats/min (Group H with HR ≥ 113 beats/min; Group L with HR < 113 beats/min). Despite similar backgrounds, including pharmacotherapy for HF, HR changes responding to titration of β-blocker (BB) therapy and myocardial interstitial fibrosis, left ventricular (LV) ejection fractions improved more significantly 1 year later in Group H than in Group L (57 % ± 11 % vs. 46 % ± 12 %, P < 0.001). Cardiac event-free survival rates were also significantly improved in Group H (P = 0.038). Multiple regression analysis revealed that only the peak HR on admission was an independent predictor of LV reverse remodeling (LVRR) 1 year later (β = 0.396, P = 0.005). High HR on first admission for ADHF is a strong predictor of LVRR, with a better prognosis in the event of NIDCM in response to optimal pharmacotherapy, independent of pre-existing myocardial damage and subsequent HR reduction by BB therapy.

Indexed as

AdultAgedCardiomyopathy, DilatedCardiovascular AgentsDisease-Free SurvivalFemaleHeart FailureHeart RateHumansMaleMiddle AgedMyocardial IschemiaPatient AdmissionRetrospective StudiesRisk FactorsStroke VolumeCardiovascular Agents

Identifiers

PMID23519525
OpenAlexW1971467155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.