Landmark analysis of DNMT3A mutations in hematological malignancies.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Association between MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: a meta-analysis based on 51 case-control studies.Medical science monitor : international medical journal of experimental and clinical research · 2015
   Pooled it
2. The Immunological Consequences of Clonal Hematopoiesis in Heart Failure.Immunological reviews · 2026
   Review
3. Clonal haematopoiesis - a novel entity that modifies pathological processes in elderly.Cell death discovery · 2023
   Review
4. YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells.Cancers · 2023
   Article
5. The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia.Cancer medicine · 2023
   Article
6. Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia enrolled in measurable residual disease-oriented trials.Haematologica · 2023
   Article
7. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis.Advances in experimental medicine and biology · 2023
   Article
8. Clonal hematopoiesis, somatic mosaicism, and age-associated disease.Physiological reviews · 2023
   Review
9. Hematopoietic Stem Cells in Wound Healing Response.Advances in wound care · 2022
   Article
10. Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation.BMC biology · 2022
    Article
11. Genetic Background of Polycythemia Vera.Genes · 2022
    Review
12. Frontiers in oncology · 2022
    Article
13. Spontaneous arising of a lymphoblastoid B-cell line harbouring a pre-leukemic DNMT3A mutation in acute myeloid leukaemia cell culture.Journal of cellular and molecular medicine · 2021
    Article
14. One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies.Epigenomes · 2021
    Review
15. Alterations toCancer research · 2021
    Review
16. Molecular and genomic landscapes in secondary & therapy related acute myeloid leukemia.American journal of blood research · 2021
    Review
17. Making it or breaking it: DNA methylation and genome integrity.Essays in biochemistry · 2020
    Review
18. DNA methyltransferases in hematological malignancies.Journal of genetics and genomics = Yi chuan xue bao · 2020
    Review
19. Landscape of Tumor Suppressor Mutations in Acute Myeloid Leukemia.Journal of clinical medicine · 2020
    Review
20. Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation.BioMed research international · 2020
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

12 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as