ReviewNutrients2013
Regulatory effects of Cu, Zn, and Ca on Fe absorption: the intricate play between nutrient transporters.
Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 58 citations in OpenAlex.
- Trial
- Changes of serum trace elements in early stage trauma and its correlation with injury severity score.Medicine · 2018Trial
- Article
- Essential Elements (Fe, Cu, Mn, Zn) in Meconium, and Newborn Length and Weight, in Relation to Maternal Lifestyle and Diet.Nutrients · 2025Article
- Associations between essential trace elements and sleep quality in Iranian adults based on the Pittsburgh Sleep Quality Index.Scientific reports · 2025Article
- Approaches to Address the Anemia Challenge.The Journal of nutrition · 2023Article
- Article
- Anemia and Associated Risk Factors in Pediatric Patients.Pediatric health, medicine and therapeutics · 2023Review
- Effect of Wheatgrass Juice on Nutritional Quality of Apple, Carrot, Beet, Orange and Lemon Juice.Foods (Basel, Switzerland) · 2022Article
- Review
- Genetic Architecture Underpinning Yield Components and Seed Mineral-Nutrients in Sesame.Genes · 2020Article
- The Role of Fe, Zn, and Cu in Pregnancy.Biomolecules · 2020Review
- Anemia of Chronic Diseases: Wider Diagnostics-Better Treatment?Nutrients · 2020Article
- Article
- Potential of Food Hydrolyzed Proteins and Peptides to Chelate Iron or Calcium and Enhance their Absorption.Foods (Basel, Switzerland) · 2018Review
- Effect of Traditional Household Processes on Iron, Zinc and Copper Bioaccessibility in Black Bean (Foods (Basel, Switzerland) · 2018Article
- Increased iron bioavailability from lactic-fermented vegetables is likely an effect of promoting the formation of ferric iron (Fe(3+)).European journal of nutrition · 2016Article
- Mineral nutrient interaction: Improving bioavailability of calcium and iron.Food science and biotechnology · 2016Review
- Iron transport through ferroportin is induced by intracellular ascorbate and involves IRP2 and HIF2α.Nutrients · 2014Article
- Multi-copper oxidases and human iron metabolism.Nutrients · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is an essential nutrient for almost every living organism because it is required in a number of biological processes that serve to maintain life. In humans, recycling of senescent erythrocytes provides most of the daily requirement of iron. In addition, we need to absorb another 1-2 mg Fe from the diet each day to compensate for losses due to epithelial sloughing, perspiration, and bleeding. Iron absorption in the intestine is mainly regulated on the enterocyte level by effectors in the diet and systemic regulators accessing the enterocyte through the basal lamina. Recently, a complex meshwork of interactions between several trace metals and regulatory proteins was revealed. This review focuses on advances in our understanding of Cu, Zn, and Ca in the regulation of iron absorption. Ascorbate as an important player is also considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.