Evidence map›Paper›PMID 23519241›Full record

ReviewChannels (Austin, Tex.)

Ion channels and information processing in GnRH neuron dendrites.

Rachael Norberg, Rebecca Campbell, Kelly J Suter

Open access · goldAbstract readReview
In one paragraph

Review in Channels (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Altered Electrophysiology and Transcriptome of GnRH Neurons in Middle-Aged Female Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. Article
  4. Cholinergic Control of GnRH Neuron Physiology and Luteinizing Hormone Secretion in Male Mice: Involvement of ACh/GABA Cotransmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Article
  6. Role of potassium channels in female reproductive system.Obstetrics & gynecology science · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Rachael NorbergDepartment of Biology, University of Texas San Antonio, San Antonio, TX, USA.
Rebecca Campbell
Kelly J Suter
Neurosciences Institute · USThe University of Texas at San Antonio · USUniversity of Otago · NZ

Funding

Control of GnRH neurons by excitatory circuitryR01HD045436 · NICHD · UNIVERSITY OF TEXAS SAN ANTONIO · PI SUTER, KELLY J · 2004 to 2012
$1.8M
NICHD NIH HHS HD-045436NICHD NIH HHS R01 HD045436
6 · The paper itself

Abstract

Recent findings indicate that a majority of action potentials originate from dendrites of GnRH neurons. This localization of the dendrite as the principle site of action potential initiation has sparked considerable interest in the nature of ionic channels throughout GnRH neurons. This paper will review the ionic conductances described within GnRH neurons and their implications for physiological output, such as sensitivity to steroids and diurnal state. To date, a majority of information regarding ionic conductances in GnRH neurons pertains to somata and the first 50-100 µm of dendrite length. Thus, unraveling the tapestry created by the nature and distribution of dendritic conductances in GnRH neurons lies at the forefront of understanding the control of reproductive hormone secretion.

Indexed as

AnimalsDendritesGonadotropin-Releasing HormoneHumansIon ChannelsGonadotropin-Releasing HormoneIon ChannelsconductancedendritesestradiolGnRH neuronshypothalamusmodelingmorphologypuberty

Identifiers

PMID23519241
PMCPMC3710340
OpenAlexW1970836023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.