SynthesisThe Journal of arthroplasty2013
Comparison of clinical outcome between simultaneous-bilateral and staged-bilateral total knee arthroplasty: a systematic review of retrospective studies.
Synthesis in The Journal of arthroplasty, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06809998 (COSTI), which is not on this map. Cited by 71 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
COSTI: COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty - A Triple Blinded, Randomized Controlled Trial Pilot Study
Who cites it
71 citing papers in PubMed, 6 syntheses or guidelines pooled it, 182 citations in OpenAlex.
- Comparing simultaneous and staged bilateral total knee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Staggered bilateral total knee arthroplasty during a single hospitalization: is it still an option? a systematic review.Musculoskeletal surgery · 2022Pooled it
- Bilateral total knee arthroplasty: Simultaneous or staged? A systematic review and meta-analysis.Medicine · 2019Pooled it
- The effectiveness and safety of tranexamic acid in bilateral total knee arthroplasty: A meta-analysis.Medicine · 2016Pooled it
- Efficacy and Safety of Tranexamic Acid in Bilateral Total Knee Replacement: A Meta-Analysis and Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2015Pooled it
- The effects of a tourniquet used in total knee arthroplasty: a meta-analysis.Journal of orthopaedic surgery and research · 2014Pooled it
- Local Efficacy of Corticosteroids as an Adjuvant for Periarticular Cocktail Injection in Simultaneous Bilateral Total Knee Arthroplasty: A Prospective Randomized Double-Blind Controlled Trial.Pain research & management · 2021Trial
- Minimally invasive and computer-assisted total knee arthroplasty versus conventional technique: a prospective, randomized study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2014Trial
- Article
- Clinical and Nonclinical Determinants of Simultaneous vs Staged Bilateral Total Knee Arthroplasty.Arthroplasty today · 2026Article
- Simultaneous bilateral total knee arthroplasty lowers reoperation and cost at the expense of higher complications and mortality: a meta-analysis and systematic review.Knee surgery & related research · 2025Review
- Simultaneous or Staged Bilateral Total Hip Arthroplasty: An Analysis of 82,897 Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Recovery after Total Knee Arthroplasty: Does one or two knees matter?Journal of clinical orthopaedics and trauma · 2025Article
- Clinical safety and efficacy of simultaneous bilateral total knee arthroplasty in an Asian population: a propensity score-matched analysis.Journal of orthopaedic surgery and research · 2025Article
- Article
- Optimal timing for the second surgery in staged bilateral total knee arthroplasty: a patient-determined interval approach.BMC surgery · 2025Article
- Simultaneous vs Staged Procedures for Bilateral Total Knee Arthroplasty: Reduced Infection, Cost, and Readmission Rates Associated With Simultaneous Procedures.Arthroplasty today · 2025Article
- Optimal timing for bilateral total knee arthroplasty: comparing simultaneous and staged procedures at various intervals: a systematic review and network meta-analysis.EFORT open reviews · 2025Article
- Simultaneous total hip and knee arthroplasties in hemophilic arthropathy: series of 5 cases.Acta orthopaedica et traumatologica turcica · 2024Article
- Comparison of clinical outcomes of bilateral and unilateral unicompartmental knee arthroplasty for the treatment of knee osteoarthritis.Scientific reports · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to conduct a systematic review assessing the clinical outcome associated with Simultaneous bilateral and staged bilateral total knee arthroplasty (TKA). A literature search for eligible studies was conducted. Eighteen retrospective comparative studies were included. Pooled results showed that the prevalence of mortality at 30 days postoperatively, pulmonary embolism, blood transfusion rate were significantly higher in simultaneous TKA group. A significantly lower rate of deep infection and revision were found in simultaneous TKA. No significant difference was seen in regard to neurological complications, deep-vein thrombosis, cardiac complications, superficial infection. Compared with staged bilateral TKA, simultaneous bilateral TKA is associated with higher rates of mortality, pulmonary embolism and blood transfusion, while decreasing the risk of deep infection and revision rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.