Evidence map›Paper›PMID 23518356›Full record

ReviewAJNR. American journal of neuroradiology

Off-label use of drugs and devices in the neuroendovascular suite.

M M Abdihalim, A E Hassan, A I Qureshi

Abstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Availability of endovascular therapies for cerebrovascular disease at primary stroke centers.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M M AbdihalimZeenat Qureshi Stroke Research Center.
A E Hassan
A I Qureshi

Funding

Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II)U01NS062091 · NINDS · UNIVERSITY OF MINNESOTA · PI QURESHI, ADNAN IQBAL · 2010 to 2014
$18.1M
Antihypertensive Treatment in Acute Cerebral HemorrhageR01NS044976 · NINDS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI QURESHI, ADNAN IQBAL · 2004 to 2006
$2.1M
NINDS NIH HHS R01 NS044976NINDS NIH HHS R01-NS44976-01A2NINDS NIH HHS U01 NS062091NINDS NIH HHS U01-NS062091- 01A2
6 · The paper itself

Abstract

summaryThe off-label use of drugs and devices in neuroendovascular procedures is common. Neurointerventionalists should be well aware of the level of evidence available in support of the off-label use of drugs and devices in their practice and some of the potential adverse events associated with them. These uses are categorized as I or II if they have been evaluated as primary or ancillary interventions in prospective trials/registries of neuroendovascular procedures and III if they were evaluated in case series. Category IV use is based on evaluation as primary or ancillary interventions in prospective trials/registries of non-neuroendovascular procedures. Physicians are allowed to use off-label drugs and procedures if there is strong evidence that they are beneficial for the patient. The neurointerventional professional societies agree that off-label use of drugs and devices is an important part of the specialty, but practicing providers should base their decisions on sound evidence when using such drugs and devices.

Indexed as

Blood Vessel ProsthesisOff-Label UseStentsCerebral RevascularizationCerebrovascular DisordersFibrinolytic AgentsFibrinolytic Agents

Identifiers

PMID23518356
PMCPMC7964838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.