Evidence map›Paper›PMID 23517235›Full record

Trial reportVox sanguinis2013

Risk factors for human immunodeficiency virus infection among Brazilian blood donors: a multicentre case-control study using audio computer-assisted structured interviews.

C de Almeida-Neto, T T Goncalez, R J Birch, S M F de Carvalho, L Capuani, S C Leão, C Miranda, P C Rocha, A B Carneiro-Proietti, B R Johnson and 4 more

Open access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Vox sanguinis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. A Systematic Review of Interventions Used to Increase Blood Donor Compliance with Deferral Criteria.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
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  5. A case-control study of risk factors for incident hepatitis B virus infection in South African blood donors.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

C de Almeida-NetoFundação Pró-Sangue/Hemocentro de São Paulo, São Paulo, Brazil.
T T Goncalez
R J Birch
S M F de Carvalho
L Capuani
S C Leão
C Miranda
P C Rocha
A B Carneiro-Proietti
B R Johnson
D J Wright
E L Murphy
B Custer
NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II) International Component, Brazil
Fundação Pró-Sangue Hemocentro de São Paulo · BRWestat (United States) · USBlood Systems Research Institute · USFundação Centro de Hematologia e Hemoterapia de Minas Gerais · BRFundação Hemopa · BRHemorio · BRSystems Research Institute · PL

Funding

REDS-II Central Laboratory-268047175-268047175N01HB047175 · HB · WESTAT. INC. · PI BUSCH, MICHAEL PAUL · 2005 to 2006
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CYTOSOLIC CA2+IONOPHORES FOR FLUORESCENCE AND L9F NMRR44HL047175 · NHLBI · COVALENT ASSOCIATES, INC. · PI LANGMUIR, MARGARET E · 1991 to 1992
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NHLBI NIH HHS HHSN268200417175CNHLBI NIH HHS N01 HB047175NHLBI NIH HHS N01-HB-47175
6 · The paper itself

Abstract

backgroundAlthough risk factors for HIV infection are known, it is important for blood centres to understand local epidemiology and disease transmission patterns. Current risk factors for HIV infection in blood donors in Brazil were assessed.

methodsA case-control study was conducted at large public blood centres located in four major cities between April 2009 and March 2011. Cases were persons whose donations were confirmed positive by enzyme immunoassays followed by Western blot confirmation. Audio computer-assisted structured interviews (ACASI) were completed by all cases and controls. Multivariable logistic regression was used to estimate adjusted odds ratios (AORs) and associated 95% confidence intervals (CIs).

resultsThere were 341 cases, including 47 with recently acquired infection, and 791 controls. Disclosed risk factors for both females and males were sex with an HIV-positive person AOR 11.3, 95% CI (4.1, 31.7) and being an IVDU or sexual partner of an IVDU [AOR 4.65 (1.8, 11.7)]. For female blood donors, additional risk factors were having male sex partners who also are MSM [AOR 13.5 (3.1, 59.8)] and having unprotected sex with multiple sexual partners [AOR 5.19 (2.1, 12.9)]. The primary risk factor for male blood donors was MSM activity [AOR 21.6 (8.8, 52.9)]. Behaviours associated with recently acquired HIV were being a MSM or sex partner of MSM [13.82, (4.7, 40.3)] and IVDU [11.47, (3.0, 43.2)].

conclusionRisk factors in blood donors parallel those in the general population in Brazil. Identified risk factors suggest that donor compliance with selection procedures at the participating blood centres is inadequate.

Indexed as

Blood DonorsHIV-1Medical AuditAdolescentBrazilCase-Control StudiesFemaleHIV InfectionsHumansMaleRisk FactorsRisk-TakingUnsafe Sexblood donorsBrazilHIVmedical informaticsrisk factorsrisk reporting/disclosure

Identifiers

PMID23517235
PMCPMC3733490
OpenAlexW1964875026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.