Evidence map›Paper›PMID 23516985›Full record

ReviewAnnual review of immunology2013

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.

Miriam Merad, Priyanka Sathe, Julie Helft, Jennifer Miller, Arthur Mortha

Abstract readComparative StudyReview
In one paragraph

Review in Annual review of immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,302 papers.

0numbers the graph read from it
0cells of the map it votes in
1,302citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,302 citing papers in PubMed.

  1. Trial
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  6. Review
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  8. The M1/M2 Test System for Determining Macrophage Phenotypes.International journal of molecular sciences · 2026
    Review
  9. Article
  10. Innate immunity: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  11. Article
  12. Tumor-Infiltrating mregDCs Restrain Anti-Tumor Immunity in Early Relapse HCC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Pulmonary Immune Cell Landscape Altered by Exposure to HIV,International journal of molecular sciences · 2026
    Article

1,242 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miriam MeradDepartment of Oncological Sciences, Mount Sinai Medical School, New York, NY 10029, USA. Miriam.merad@mssm.edu
Priyanka Sathe
Julie Helft
Jennifer Miller
Arthur Mortha

Funding

Contribution of the cutaneous APC network to melanoma progression and therapy.R01CA173861 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MERAD, MIRIAM · 2013 to 2017
$2.1M
Role of Mucosal DC Subsets in the Control of Influenza A Virus ImmunityU01AI095611 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MERAD, MIRIAM, PALUCKA, ANNA KAROLINA · 2011 to 2015
$1.8M
NCI NIH HHS R01 CA173861NIAID NIH HHS U01 AI095611
6 · The paper itself

Abstract

Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, establishing the DC system as a unique hematopoietic branch. Recent work has also established that tissue DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte function. This review discusses major advances in our understanding of the regulation of DC lineage commitment, differentiation, diversification, and function in situ.

Indexed as

AnimalsCell DifferentiationCell LineageCell MovementDendritic CellsHumansInflammationInflammation MediatorsLymphoid TissueInflammation Mediators

Identifiers

PMID23516985
PMCPMC3853342

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.